SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3r4q LACTOYLGLUTATHIONE
LYASE
(Agrobacterium
fabrum) 		4 / 7 TYR A  26
VAL A  29
ILE A 119
ASP A 121
 None
 1.17A 2x45B-3r4qA:
undetectable		 2x45B-3r4qA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3r4q LACTOYLGLUTATHIONE
LYASE
(Agrobacterium
fabrum) 		4 / 7 TYR A  26
VAL A  29
ILE A 119
ASP A 121
 None
 1.17A 2x45C-3r4qA:
undetectable		 2x45C-3r4qA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 3r4q LACTOYLGLUTATHIONE
LYASE
(Agrobacterium
fabrum) 		4 / 7 TYR A  26
VAL A  29
ILE A 119
ASP A 121
 None
 1.10A 3bu1A-3r4qA:
undetectable		 3bu1A-3r4qA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3r4q LACTOYLGLUTATHIONE
LYASE
(Agrobacterium
fabrum) 		5 / 12 LEU A  32
PHE A  82
ALA A  13
ALA A  16
GLY A 124
 None
 1.01A 5veuA-3r4qA:
undetectable		 5veuA-3r4qA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 3r4q LACTOYLGLUTATHIONE
LYASE
(Agrobacterium
fabrum) 		4 / 5 PHE A  30
VAL A  43
PRO A 122
VAL A  29
 None
 1.11A 6ekzA-3r4qA:
undetectable		 6ekzA-3r4qA:
17.50