SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 7 SER A 239
SER A 223
ALA A 155
ILE A 154
 None
None
EDO  A 325 (-3.8A)
EDO  A 325 ( 4.4A)
 1.07A 1fxhA-3r4rA:
undetectable
1fxhB-3r4rA:
undetectable		 1fxhA-3r4rA:
21.65
1fxhB-3r4rA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 6 LEU A  40
LEU A  43
LEU A 187
CYH A  69
 None
 0.99A 2ab2A-3r4rA:
undetectable		 2ab2A-3r4rA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 5 LEU A  40
LEU A  43
LEU A 187
CYH A  69
 None
 0.99A 2ab2B-3r4rA:
undetectable		 2ab2B-3r4rA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		5 / 9 GLU A 311
ASN A 306
ILE A 284
ALA A 232
VAL A 233
 None
 1.36A 2drdA-3r4rA:
undetectable		 2drdA-3r4rA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 6 LEU A 187
SER A 134
PHE A 136
ASP A 137
 None
 1.06A 2vn1B-3r4rA:
undetectable		 2vn1B-3r4rA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 8 VAL A 249
LEU A 207
GLY A 198
TYR A 200
 SO4  A 319 (-3.7A)
None
None
None
 0.99A 3af0A-3r4rA:
undetectable		 3af0A-3r4rA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		5 / 8 ALA A  72
LEU A 123
ASP A 137
TYR A 149
SER A 134
 None
 1.49A 3qj7A-3r4rA:
undetectable
3qj7D-3r4rA:
undetectable		 3qj7A-3r4rA:
22.26
3qj7D-3r4rA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 4 LEU A  64
LEU A  43
GLN A  67
GLU A  93
 None
 1.23A 4i41A-3r4rA:
undetectable		 4i41A-3r4rA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 7 PHE A 136
ILE A 154
TYR A 254
ASN A  68
 None
EDO  A 325 ( 4.4A)
None
None
 1.32A 4o7gA-3r4rA:
undetectable
4o7gB-3r4rA:
undetectable		 4o7gA-3r4rA:
22.55
4o7gB-3r4rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 6 PHE A 136
ILE A 154
TYR A 254
ASN A  68
 None
EDO  A 325 ( 4.4A)
None
None
 1.48A 4o7gB-3r4rA:
undetectable		 4o7gB-3r4rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		3 / 3 THR A 140
ASN A 147
SER A 148
 None
 0.69A 4tvtA-3r4rA:
undetectable		 4tvtA-3r4rA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		4 / 7 LEU A 187
GLU A  63
ILE A 154
VAL A 165
 None
None
EDO  A 325 ( 4.4A)
None
 1.09A 5jh7C-3r4rA:
undetectable		 5jh7C-3r4rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3r4r HYPOTHETICAL
FIMBRIAL ASSEMBLY
PROTEIN
(Parabacteroides
distasonis) 		5 / 8 LEU A 219
VAL A 216
VAL A 263
PHE A 278
ILE A 194
 None
 1.40A 5y9mA-3r4rA:
undetectable		 5y9mA-3r4rA:
13.51