SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.27A 1q23B-3r4vA:
undetectable
1q23B-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.27A 1q23C-3r4vA:
undetectable
1q23C-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.19A 1q23D-3r4vA:
undetectable
1q23E-3r4vA:
undetectable
1q23D-3r4vA:
18.99
1q23E-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 10 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.21A 1q23E-3r4vA:
undetectable
1q23E-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.26A 1q23F-3r4vA:
undetectable
1q23F-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.10A 1q23G-3r4vA:
undetectable
1q23G-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.23A 1q23I-3r4vA:
undetectable
1q23I-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.24A 1q23J-3r4vA:
undetectable
1q23J-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 10 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.25A 1q23K-3r4vA:
undetectable
1q23K-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.22A 1q23L-3r4vA:
undetectable
1q23L-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
4 / 7 ILE A  63
ILE A 102
LEU A  74
ILE A  71
None
0.74A 2q83A-3r4vA:
undetectable
2q83A-3r4vA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 ILE A 102
ALA A  81
VAL A   3
THR A  77
PHE A  31
None
1.23A 2qo4A-3r4vA:
undetectable
2qo4A-3r4vA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 ILE A 102
ALA A  81
VAL A   3
THR A  77
PHE A  31
None
1.22A 2qo6A-3r4vA:
undetectable
2qo6A-3r4vA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A  94
THR A  50
ALA A  10
GLY A  11
MET A  15
GDP  A 400 (-3.8A)
None
None
GDP  A 400 (-3.4A)
None
1.22A 2xf3A-3r4vA:
undetectable
2xf3A-3r4vA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A  94
THR A  50
ALA A  10
GLY A  11
MET A  15
GDP  A 400 (-3.8A)
None
None
GDP  A 400 (-3.4A)
None
1.22A 2xf3B-3r4vA:
undetectable
2xf3B-3r4vA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A  94
THR A  50
ALA A  10
GLY A  11
MET A  15
GDP  A 400 (-3.8A)
None
None
GDP  A 400 (-3.4A)
None
1.22A 2xh9A-3r4vA:
undetectable
2xh9A-3r4vA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
4 / 5 VAL A 175
VAL A 176
GLN A 181
PHE A 113
None
1.32A 3bjwH-3r4vA:
undetectable
3bjwH-3r4vA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 GLU A 167
ILE A 164
ASN A 165
LEU A 211
GLU A 210
None
GDP  A 400 (-3.7A)
GDP  A 400 (-2.9A)
None
None
1.17A 3ckkA-3r4vA:
3.8
3ckkA-3r4vA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 PHE A   9
VAL A 149
VAL A  17
LEU A  21
ILE A 168
None
1.14A 3elzA-3r4vA:
undetectable
3elzA-3r4vA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
3 / 3 ARG A 196
VAL A  86
THR A 103
None
0.82A 3ndtA-3r4vA:
undetectable
3ndtA-3r4vA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
4 / 8 TYR A 161
ILE A 164
VAL A 118
THR A  13
GDP  A 400 (-3.7A)
GDP  A 400 (-3.7A)
GDP  A 400 (-4.6A)
GDP  A 400 (-3.5A)
0.82A 3p4wC-3r4vA:
undetectable
3p4wC-3r4vA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.21A 3u9fB-3r4vA:
undetectable
3u9fC-3r4vA:
undetectable
3u9fB-3r4vA:
18.99
3u9fC-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.15A 3u9fH-3r4vA:
undetectable
3u9fI-3r4vA:
undetectable
3u9fH-3r4vA:
18.99
3u9fI-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.15A 3u9fN-3r4vA:
undetectable
3u9fO-3r4vA:
undetectable
3u9fN-3r4vA:
18.99
3u9fO-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 9 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.14A 3u9fP-3r4vA:
undetectable
3u9fP-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 10 SER A 228
TYR A 247
LEU A 178
VAL A 179
PHE A  83
None
1.17A 3u9fR-3r4vA:
undetectable
3u9fR-3r4vA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 PHE A   9
ASN A 155
ALA A 120
GLY A 119
LEU A  90
None
GDP  A 400 (-3.1A)
GDP  A 400 (-3.4A)
None
None
1.44A 4oadA-3r4vA:
undetectable
4oadA-3r4vA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 LEU A 101
LEU A  98
GLY A  99
ILE A 148
VAL A 208
None
1.09A 4ok1A-3r4vA:
undetectable
4ok1A-3r4vA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
4 / 7 GLU A 167
SER A 163
VAL A 118
PHE A 116
None
None
GDP  A 400 (-4.6A)
None
1.04A 4wnvD-3r4vA:
undetectable
4wnvD-3r4vA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 VAL A 260
HIS A 183
PHE A 267
LEU A 230
ARG A 173
None
1.35A 5hnxB-3r4vA:
20.8
5hnxB-3r4vA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 12 ASN A 165
ILE A 168
ALA A 169
VAL A 118
GLY A 119
GDP  A 400 (-2.9A)
None
None
GDP  A 400 (-4.6A)
None
0.77A 5j2tC-3r4vA:
19.7
5j2tC-3r4vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
5 / 11 ILE A 213
ASP A 262
THR A 261
VAL A 179
LEU A 232
None
1.33A 5jkwA-3r4vA:
undetectable
5jkwA-3r4vA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
4 / 6 VAL A 208
VAL A 117
SER A 115
ILE A 172
None
1.08A 5jw1B-3r4vA:
undetectable
5jw1B-3r4vA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)
3r4v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
phage
201phi2-1)
4 / 8 TYR A 161
ILE A 164
VAL A 118
THR A  13
GDP  A 400 (-3.7A)
GDP  A 400 (-3.7A)
GDP  A 400 (-4.6A)
GDP  A 400 (-3.5A)
0.83A 5mzrE-3r4vA:
undetectable
5mzrE-3r4vA:
16.60