SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r4z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 6 PHE A 126
ILE A  49
LYS A  91
ALA A 124
None
1.19A 1hk2A-3r4zA:
undetectable
1hk2A-3r4zA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
5 / 11 PHE A 313
ALA A  55
VAL A 140
LEU A 139
LEU A  57
None
0.97A 1jinA-3r4zA:
undetectable
1jinA-3r4zA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
5 / 12 PHE A 313
ALA A  55
VAL A 140
LEU A 139
LEU A  57
None
0.92A 1jipA-3r4zA:
undetectable
1jipA-3r4zA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 4 ASP A 282
HIS A 264
ARG A 235
GLU A 224
None
GLA  A 375 (-4.0A)
GLA  A 375 (-2.8A)
GLA  A 375 (-2.9A)
1.30A 1lqtA-3r4zA:
undetectable
1lqtA-3r4zA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 8 LEU A 210
ALA A 242
ILE A 243
GLY A 249
None
0.84A 1sv9A-3r4zA:
undetectable
1sv9A-3r4zA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.26A 1zzrA-3r4zA:
undetectable
1zzrB-3r4zA:
undetectable
1zzrA-3r4zA:
20.63
1zzrB-3r4zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.25A 1zzrA-3r4zA:
undetectable
1zzrB-3r4zA:
undetectable
1zzrA-3r4zA:
20.63
1zzrB-3r4zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.25A 1zzuA-3r4zA:
undetectable
1zzuB-3r4zA:
undetectable
1zzuA-3r4zA:
20.63
1zzuB-3r4zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.24A 1zzuA-3r4zA:
undetectable
1zzuB-3r4zA:
undetectable
1zzuA-3r4zA:
20.63
1zzuB-3r4zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1162_1
(ALLERGEN ARG R 1)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 4 GLU A 309
ASP A 282
HIS A 264
GLU A 265
None
None
GLA  A 375 (-4.0A)
GLA  A 375 ( 4.4A)
1.23A 2x45A-3r4zA:
0.0
2x45A-3r4zA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.28A 3dqrA-3r4zA:
undetectable
3dqrB-3r4zA:
undetectable
3dqrA-3r4zA:
20.59
3dqrB-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.21A 3dqrA-3r4zA:
undetectable
3dqrB-3r4zA:
undetectable
3dqrA-3r4zA:
20.59
3dqrB-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.23A 3jx2A-3r4zA:
undetectable
3jx2B-3r4zA:
undetectable
3jx2A-3r4zA:
20.59
3jx2B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.22A 3jx2A-3r4zA:
undetectable
3jx2B-3r4zA:
undetectable
3jx2A-3r4zA:
20.59
3jx2B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.23A 3jx3A-3r4zA:
undetectable
3jx3B-3r4zA:
undetectable
3jx3A-3r4zA:
20.59
3jx3B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.23A 3jx3A-3r4zA:
undetectable
3jx3B-3r4zA:
undetectable
3jx3A-3r4zA:
20.59
3jx3B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.26A 3jx4A-3r4zA:
undetectable
3jx4B-3r4zA:
undetectable
3jx4A-3r4zA:
20.59
3jx4B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.26A 3jx5A-3r4zA:
undetectable
3jx5B-3r4zA:
undetectable
3jx5A-3r4zA:
20.59
3jx5B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.25A 3jx5A-3r4zA:
undetectable
3jx5B-3r4zA:
undetectable
3jx5A-3r4zA:
20.59
3jx5B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.23A 3jx6A-3r4zA:
undetectable
3jx6B-3r4zA:
undetectable
3jx6A-3r4zA:
20.81
3jx6B-3r4zA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.22A 3jx6A-3r4zA:
undetectable
3jx6B-3r4zA:
undetectable
3jx6A-3r4zA:
20.81
3jx6B-3r4zA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 8 TYR A 148
PHE A 126
GLN A 142
ASP A 207
None
0.89A 3mjrD-3r4zA:
undetectable
3mjrD-3r4zA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 6 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.18A 3n61A-3r4zA:
undetectable
3n61B-3r4zA:
undetectable
3n61A-3r4zA:
20.59
3n61B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.20A 3n61A-3r4zA:
undetectable
3n61B-3r4zA:
undetectable
3n61A-3r4zA:
20.59
3n61B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.23A 3nljA-3r4zA:
undetectable
3nljB-3r4zA:
undetectable
3nljA-3r4zA:
20.81
3nljB-3r4zA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.21A 3nljA-3r4zA:
undetectable
3nljB-3r4zA:
undetectable
3nljA-3r4zA:
20.81
3nljB-3r4zA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.28A 3nlpA-3r4zA:
undetectable
3nlpB-3r4zA:
undetectable
3nlpA-3r4zA:
20.59
3nlpB-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.21A 3nlqA-3r4zA:
undetectable
3nlqB-3r4zA:
undetectable
3nlqA-3r4zA:
20.59
3nlqB-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 5 VAL A  48
GLY A  47
TYR A  44
ASP A 336
None
1.24A 3w9tA-3r4zA:
undetectable
3w9tA-3r4zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 5 VAL A  48
GLY A  47
TYR A  44
ASP A 336
None
1.24A 3w9tB-3r4zA:
undetectable
3w9tB-3r4zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 5 VAL A  48
GLY A  47
TYR A  44
ASP A 336
None
1.24A 3w9tC-3r4zA:
undetectable
3w9tC-3r4zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 5 VAL A  48
GLY A  47
TYR A  44
ASP A 336
None
1.23A 3w9tD-3r4zA:
0.0
3w9tD-3r4zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 5 VAL A  48
GLY A  47
TYR A  44
ASP A 336
None
1.24A 3w9tE-3r4zA:
undetectable
3w9tE-3r4zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 5 VAL A  48
GLY A  47
TYR A  44
ASP A 336
None
1.24A 3w9tF-3r4zA:
undetectable
3w9tF-3r4zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 5 VAL A  48
GLY A  47
TYR A  44
ASP A 336
None
1.23A 3w9tG-3r4zA:
undetectable
3w9tG-3r4zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 HIS A 264
ASP A  52
HIS A 206
HIS A 333
GLA  A 375 (-4.0A)
None
None
None
1.20A 3zodA-3r4zA:
undetectable
3zodA-3r4zA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
5 / 12 ASP A  84
GLY A  76
GLY A  78
SER A  79
GLY A  72
None
1.20A 4blvB-3r4zA:
undetectable
4blvB-3r4zA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.25A 4cx3A-3r4zA:
undetectable
4cx3B-3r4zA:
undetectable
4cx3A-3r4zA:
20.59
4cx3B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.25A 4cx3A-3r4zA:
undetectable
4cx3B-3r4zA:
undetectable
4cx3A-3r4zA:
20.59
4cx3B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.26A 4cx4A-3r4zA:
undetectable
4cx4B-3r4zA:
undetectable
4cx4A-3r4zA:
20.59
4cx4B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.27A 4cx4A-3r4zA:
undetectable
4cx4B-3r4zA:
undetectable
4cx4A-3r4zA:
20.59
4cx4B-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.26A 5addA-3r4zA:
undetectable
5addB-3r4zA:
undetectable
5addA-3r4zA:
20.59
5addB-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.30A 5adeA-3r4zA:
undetectable
5adeB-3r4zA:
undetectable
5adeA-3r4zA:
20.59
5adeB-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 VAL A 130
VAL A  94
TRP A  66
GLU A 129
None
1.22A 5g0pA-3r4zA:
undetectable
5g0pB-3r4zA:
undetectable
5g0pA-3r4zA:
20.59
5g0pB-3r4zA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans)
4 / 7 GLU A 129
VAL A 130
VAL A  94
TRP A  66
None
1.22A 5g0pA-3r4zA:
undetectable
5g0pB-3r4zA:
undetectable
5g0pA-3r4zA:
20.59
5g0pB-3r4zA:
20.59