SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r50'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		3 / 3 ASP A  81
ASP A  83
ASN A  57
 None
 0.85A 2bm9D-3r50A:
undetectable		 2bm9D-3r50A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		4 / 6 GLY A 116
PHE A  39
PRO A  43
THR A  46
 None
 1.25A 2m2oB-3r50A:
undetectable		 2m2oB-3r50A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		5 / 11 LEU A  32
LEU A  37
ILE A 100
VAL A  64
ILE A  62
 None
 1.22A 2uxoB-3r50A:
undetectable		 2uxoB-3r50A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		5 / 12 GLY A 148
GLY A  14
ILE A  84
GLY A 135
LEU A  32
 None
 0.98A 4n48A-3r50A:
undetectable		 4n48A-3r50A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		5 / 12 GLY A 148
GLY A  14
ILE A  84
GLY A 135
LEU A  32
 None
 0.96A 4n48B-3r50A:
undetectable		 4n48B-3r50A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		5 / 9 VAL A 144
VAL A  64
PHE A  54
ILE A  35
LEU A  49
 None
 1.48A 5e4dA-3r50A:
undetectable		 5e4dA-3r50A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		4 / 4 GLU A  76
THR A  77
THR A  63
LEU A  72
 None
 0.91A 5v96A-3r50A:
undetectable		 5v96A-3r50A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		4 / 4 GLU A  76
THR A  77
THR A  63
LEU A  72
 None
 0.91A 5v96B-3r50A:
undetectable		 5v96B-3r50A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		4 / 4 GLU A  76
THR A  77
THR A  63
LEU A  72
 None
 0.95A 5v96C-3r50A:
undetectable		 5v96C-3r50A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3r50 IPOMOELIN
(Ipomoea
batatas) 		4 / 4 GLU A  76
THR A  77
THR A  63
LEU A  72
 None
 0.95A 5v96D-3r50A:
undetectable		 5v96D-3r50A:
17.93