SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG1_A_SPMA999_1 (TYROSYL-DNA PHOSPHODIESTERASE 1)	3r5z	PUTATIVE UNCHARACTERIZED PROTEIN (Nocardia farcinica)	3 / 3	TRP A 80 VAL A 79 PRO A 78	F42 A 201 (-4.4A) F42 A 201 (-3.7A) F42 A 201 (-4.4A)	1.00A	1rg1A-3r5zA: undetectable	1rg1A-3r5zA: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RH0_A_SPMA999_1 (TYROSYL-DNA PHOSPHODIESTERASE 1)	3r5z	PUTATIVE UNCHARACTERIZED PROTEIN (Nocardia farcinica)	3 / 3	TRP A 80 VAL A 79 PRO A 78	F42 A 201 (-4.4A) F42 A 201 (-3.7A) F42 A 201 (-4.4A)	1.00A	1rh0A-3r5zA: undetectable	1rh0A-3r5zA: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QF1_A_PZEA6951_1 (LACTOPEROXIDASE)	3r5z	PUTATIVE UNCHARACTERIZED PROTEIN (Nocardia farcinica)	3 / 3	HIS A 77 ARG A 134 GLU A 135	None	0.85A	3qf1A-3r5zA: undetectable	3qf1A-3r5zA: 13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BBO_C_ACTC1113_0 (BLR5658 PROTEIN)	3r5z	PUTATIVE UNCHARACTERIZED PROTEIN (Nocardia farcinica)	4 / 4	ASN A 83 ALA A 46 GLY A 45 THR A 48	F42 A 201 (-3.3A) F42 A 201 (-3.7A) F42 A 201 (-3.6A) F42 A 201 (-2.8A)	1.09A	4bboC-3r5zA: undetectable	4bboC-3r5zA: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RG1_A_SPMA999_1","TYROSYL-DNA PHOSPHODIESTERASE 1","3r5z","PUTATIVE UNCHARACTERIZED PROTEIN","Nocardia farcinica",3,"TRP A  80;VAL A  79;PRO A  78","F42 A 201 (-4.4A);F42 A 201 (-3.7A);F42 A 201 (-4.4A)","1.00A","1rg1A-3r5zA:undetectable","1rg1A-3r5zA:16.74"],["1RH0_A_SPMA999_1","TYROSYL-DNA PHOSPHODIESTERASE 1","3r5z","PUTATIVE UNCHARACTERIZED PROTEIN","Nocardia farcinica",3,"TRP A  80;VAL A  79;PRO A  78","F42 A 201 (-4.4A);F42 A 201 (-3.7A);F42 A 201 (-4.4A)","1.00A","1rh0A-3r5zA:undetectable","1rh0A-3r5zA:16.74"],["3QF1_A_PZEA6951_1","LACTOPEROXIDASE","3r5z","PUTATIVE UNCHARACTERIZED PROTEIN","Nocardia farcinica",3,"HIS A  77;ARG A 134;GLU A 135","None","0.85A","3qf1A-3r5zA:undetectable","3qf1A-3r5zA:13.24"],["4BBO_C_ACTC1113_0","BLR5658 PROTEIN","3r5z","PUTATIVE UNCHARACTERIZED PROTEIN","Nocardia farcinica",4,"ASN A  83;ALA A  46;GLY A  45;THR A  48","F42 A 201 (-3.3A);F42 A 201 (-3.7A);F42 A 201 (-3.6A);F42 A 201 (-2.8A)","1.09A","4bboC-3r5zA:undetectable","4bboC-3r5zA:21.43"]]