SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 258
ALA A 308
ASP A 263
GLY A 306
 None
 1.11A 1e7cA-3r67A:
undetectable		 1e7cA-3r67A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 260
ASP A 295
SER A 264
 None
 0.65A 2qhfA-3r67A:
undetectable		 2qhfA-3r67A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLU A 334
GLY A 361
PRO A  75
ARG A  40
LYS A 335
 None
 1.37A 3bjwD-3r67A:
undetectable		 3bjwD-3r67A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 258
GLY A 294
ALA A 305
GLY A 306
ASN A 285
 None
EDO  A 389 ( 3.7A)
None
None
None
 1.22A 3v3oA-3r67A:
undetectable		 3v3oA-3r67A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 328
PRO A 329
GLY A 361
ALA A 305
 EDO  A 384 ( 3.9A)
None
None
None
 0.97A 4g0uB-3r67A:
undetectable		 4g0uB-3r67A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 280
VAL A 232
LEU A 238
VAL A 154
ILE A 214
 None
 1.02A 5mugA-3r67A:
undetectable		 5mugA-3r67A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 185
ASN A 240
ARG A 192
GLY A 191
 None
 1.08A 5o4yA-3r67A:
undetectable		 5o4yA-3r67A:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 182
ASP A 237
TRP A 241
TYR A 181
 None
 1.35A 6ag0A-3r67A:
undetectable		 6ag0A-3r67A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 182
ASP A 237
TRP A 241
TYR A 181
 None
 1.33A 6ag0C-3r67A:
undetectable		 6ag0C-3r67A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 3r67 PUTATIVE GLYCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 4 LEU A 105
ASP A 142
PRO A 143
ARG A  89
 None
EDO  A 382 ( 4.7A)
None
None
 1.10A 6fgdA-3r67A:
undetectable		 6fgdA-3r67A:
21.95