SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O1C_A_ADNA127_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	6 / 10	ILE A 5 PHE A 6 ASP A 28 LEU A 38 HIS A 91 HIS A 93	None MPD A 134 ( 4.9A) MPD A 134 (-3.3A) None SO4 A 133 (-3.6A) SO4 A 133 (-4.3A)	0.33A	3o1cA-3r6fA: 14.3	3o1cA-3r6fA: 27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O1X_A_ADNA1450_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	6 / 10	ILE A 5 PHE A 6 ASP A 28 LEU A 38 HIS A 91 HIS A 93	None MPD A 134 ( 4.9A) MPD A 134 (-3.3A) None SO4 A 133 (-3.6A) SO4 A 133 (-4.3A)	0.34A	3o1xA-3r6fA: 14.2	3o1xA-3r6fA: 27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QGZ_A_ADNA127_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	6 / 10	ILE A 5 PHE A 6 ASP A 28 LEU A 38 HIS A 91 HIS A 93	None MPD A 134 ( 4.9A) MPD A 134 (-3.3A) None SO4 A 133 (-3.6A) SO4 A 133 (-4.3A)	0.33A	3qgzA-3r6fA: 14.4	3qgzA-3r6fA: 27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	4 / 8	ASN A 80 GLN A 85 HIS A 91 HIS A 93	SO4 A 133 (-3.7A) None SO4 A 133 (-3.6A) SO4 A 133 (-4.3A)	0.27A	5km8A-3r6fA: 12.4 5km8B-3r6fA: 14.5	5km8A-3r6fA: 22.89 5km8B-3r6fA: 22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM9_B_ADNB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	5 / 12	ILE A 5 PHE A 6 ASP A 28 LEU A 38 VAL A 87	None MPD A 134 ( 4.9A) MPD A 134 (-3.3A) None SO4 A 133 (-4.4A)	0.58A	5km9B-3r6fA: 14.5	5km9B-3r6fA: 22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM9_B_ADNB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	6 / 12	PHE A 6 ASP A 28 LEU A 38 VAL A 87 HIS A 91 HIS A 93	MPD A 134 ( 4.9A) MPD A 134 (-3.3A) None SO4 A 133 (-4.4A) SO4 A 133 (-3.6A) SO4 A 133 (-4.3A)	0.40A	5km9B-3r6fA: 14.5	5km9B-3r6fA: 22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UVM_B_ADNB207_1 (HISTIDINE TRIAD (HIT) PROTEIN)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	6 / 12	PHE A 6 ASP A 28 LEU A 38 VAL A 87 HIS A 91 HIS A 93	MPD A 134 ( 4.9A) MPD A 134 (-3.3A) None SO4 A 133 (-4.4A) SO4 A 133 (-3.6A) SO4 A 133 (-4.3A)	0.40A	5uvmB-3r6fA: 14.7	5uvmB-3r6fA: 25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UVM_B_ADNB207_1 (HISTIDINE TRIAD (HIT) PROTEIN)	3r6f	HIT FAMILY PROTEIN (Encephalitozoon cuniculi)	5 / 12	VAL A 87 ILE A 40 LEU A 38 HIS A 93 HIS A 36	SO4 A 133 (-4.4A) None None SO4 A 133 (-4.3A) None	0.90A	5uvmB-3r6fA: 14.7	5uvmB-3r6fA: 25.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3O1C_A_ADNA127_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",6,"ILE A   5;PHE A   6;ASP A  28;LEU A  38;HIS A  91;HIS A  93","None;MPD A 134 ( 4.9A);MPD A 134 (-3.3A);None;SO4 A 133 (-3.6A);SO4 A 133 (-4.3A)","0.33A","3o1cA-3r6fA:14.3","3o1cA-3r6fA:27.39"],["3O1X_A_ADNA1450_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",6,"ILE A   5;PHE A   6;ASP A  28;LEU A  38;HIS A  91;HIS A  93","None;MPD A 134 ( 4.9A);MPD A 134 (-3.3A);None;SO4 A 133 (-3.6A);SO4 A 133 (-4.3A)","0.34A","3o1xA-3r6fA:14.2","3o1xA-3r6fA:27.39"],["3QGZ_A_ADNA127_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 1","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",6,"ILE A   5;PHE A   6;ASP A  28;LEU A  38;HIS A  91;HIS A  93","None;MPD A 134 ( 4.9A);MPD A 134 (-3.3A);None;SO4 A 133 (-3.6A);SO4 A 133 (-4.3A)","0.33A","3qgzA-3r6fA:14.4","3qgzA-3r6fA:27.39"],["5KM8_B_L8PB201_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL;HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",4,"ASN A  80;GLN A  85;HIS A  91;HIS A  93","SO4 A 133 (-3.7A);None;SO4 A 133 (-3.6A);SO4 A 133 (-4.3A)","0.27A","5km8A-3r6fA:12.4;5km8B-3r6fA:14.5","5km8A-3r6fA:22.89;5km8B-3r6fA:22.89"],["5KM9_B_ADNB201_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",5,"ILE A   5;PHE A   6;ASP A  28;LEU A  38;VAL A  87","None;MPD A 134 ( 4.9A);MPD A 134 (-3.3A);None;SO4 A 133 (-4.4A)","0.58A","5km9B-3r6fA:14.5","5km9B-3r6fA:22.89"],["5KM9_B_ADNB201_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",6,"PHE A   6;ASP A  28;LEU A  38;VAL A  87;HIS A  91;HIS A  93","MPD A 134 ( 4.9A);MPD A 134 (-3.3A);None;SO4 A 133 (-4.4A);SO4 A 133 (-3.6A);SO4 A 133 (-4.3A)","0.40A","5km9B-3r6fA:14.5","5km9B-3r6fA:22.89"],["5UVM_B_ADNB207_1","HISTIDINE TRIAD (HIT) PROTEIN","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",6,"PHE A   6;ASP A  28;LEU A  38;VAL A  87;HIS A  91;HIS A  93","MPD A 134 ( 4.9A);MPD A 134 (-3.3A);None;SO4 A 133 (-4.4A);SO4 A 133 (-3.6A);SO4 A 133 (-4.3A)","0.40A","5uvmB-3r6fA:14.7","5uvmB-3r6fA:25.73"],["5UVM_B_ADNB207_1","HISTIDINE TRIAD (HIT) PROTEIN","3r6f","HIT FAMILY PROTEIN","Encephalitozoon cuniculi",5,"VAL A  87;ILE A  40;LEU A  38;HIS A  93;HIS A  36","SO4 A 133 (-4.4A);None;None;SO4 A 133 (-4.3A);None","0.90A","5uvmB-3r6fA:14.7","5uvmB-3r6fA:25.73"]]