SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3r6m YEAZ, RESUSCITATION
PROMOTING FACTOR
(Vibrio
parahaemolyticus) 		4 / 7 PRO A 190
ILE A 195
PRO A  66
GLY A  65
 None
 0.98A 2y7kA-3r6mA:
undetectable		 2y7kA-3r6mA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3r6m YEAZ, RESUSCITATION
PROMOTING FACTOR
(Vibrio
parahaemolyticus) 		3 / 3 VAL A  46
VAL A 196
SER A 192
 None
 0.59A 3n8xB-3r6mA:
undetectable		 3n8xB-3r6mA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 3r6m YEAZ, RESUSCITATION
PROMOTING FACTOR
(Vibrio
parahaemolyticus) 		4 / 7 PRO A 190
ASP A 191
SER A 192
SER A  15
 None
 1.21A 4k7gB-3r6mA:
undetectable		 4k7gB-3r6mA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3r6m YEAZ, RESUSCITATION
PROMOTING FACTOR
(Vibrio
parahaemolyticus) 		5 / 12 VAL A  16
LEU A   5
ILE A  78
GLY A  81
LEU A  54
 None
 1.02A 4y8wC-3r6mA:
undetectable		 4y8wC-3r6mA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3r6m YEAZ, RESUSCITATION
PROMOTING FACTOR
(Vibrio
parahaemolyticus) 		6 / 12 ALA A  86
LEU A  88
VAL A 211
GLY A  77
THR A   9
LEU A  40
 None
 1.47A 5x24A-3r6mA:
undetectable		 5x24A-3r6mA:
18.16