SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r75'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 9 LEU A 512
ILE A 516
VAL A 586
GLY A 602
LEU A 536
 None
 1.12A 1e7aB-3r75A:
undetectable		 1e7aB-3r75A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		9 / 11 GLU A 201
ILE A 216
GLY A 218
THR A 219
GLU A 244
HIS A 279
ARG A 352
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.2A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
PYR  A 702 ( 3.9A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.41A 1i7qA-3r75A:
37.7		 1i7qA-3r75A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		9 / 10 GLU A 201
ILE A 216
GLY A 218
THR A 219
GLU A 244
HIS A 279
ARG A 352
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.2A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
PYR  A 702 ( 3.9A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.39A 1i7qC-3r75A:
33.9		 1i7qC-3r75A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 GLU A 355
ILE A 364
LEU A 390
TYR A 163
THR A 190
 None
 1.24A 1jomA-3r75A:
undetectable		 1jomA-3r75A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 ASP A 357
ARG A 193
GLY A 365
THR A 155
GLY A 158
 None
 1.39A 1jr1A-3r75A:
undetectable		 1jr1A-3r75A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 ASP A 581
GLY A 537
ILE A 538
ILE A 516
 None
 0.59A 1n49A-3r75A:
undetectable		 1n49A-3r75A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 6 ASP A 581
GLY A 537
ILE A 538
ILE A 516
 None
 0.62A 1n49D-3r75A:
undetectable		 1n49D-3r75A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 7 THR A 314
GLU A 321
THR A 306
SER A 329
VAL A  72
 None
 1.21A 1tv8A-3r75A:
undetectable		 1tv8A-3r75A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 GLU A 321
THR A 306
SER A 329
VAL A  72
 None
 1.02A 1tv8B-3r75A:
undetectable		 1tv8B-3r75A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 THR A 314
GLU A 321
SER A 329
VAL A  72
 None
 1.12A 1tv8B-3r75A:
undetectable		 1tv8B-3r75A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 ILE A 516
VAL A 580
GLY A 584
LEU A 536
SER A 607
 None
 1.18A 2bxeA-3r75A:
undetectable		 2bxeA-3r75A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 LEU A 512
ILE A 516
VAL A 586
GLY A 602
LEU A 536
 None
 1.14A 2bxeA-3r75A:
undetectable		 2bxeA-3r75A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 ILE A 516
VAL A 580
GLY A 584
LEU A 536
SER A 607
 None
 1.13A 2bxeB-3r75A:
undetectable		 2bxeB-3r75A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 LEU A 512
ILE A 516
VAL A 586
GLY A 602
LEU A 536
 None
 1.13A 2bxeB-3r75A:
undetectable		 2bxeB-3r75A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 9 LEU A  53
LEU A  50
LEU A 345
ARG A 343
ILE A 335
 None
 1.23A 2f78A-3r75A:
undetectable		 2f78A-3r75A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 9 LEU A  23
ILE A  37
PHE A 172
LEU A 108
ILE A 111
 None
 1.24A 2f7aA-3r75A:
undetectable		 2f7aA-3r75A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 9 LEU A  53
LEU A  50
LEU A 345
ARG A 343
ILE A 335
 None
 1.09A 2f7aB-3r75A:
undetectable		 2f7aB-3r75A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 8 THR A 314
GLU A 321
THR A 306
SER A 329
VAL A  72
 None
 1.16A 2fb2A-3r75A:
undetectable		 2fb2A-3r75A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 GLU A 321
THR A 306
SER A 329
VAL A  72
 None
 1.02A 2fb2B-3r75A:
2.1		 2fb2B-3r75A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 THR A 314
GLU A 321
SER A 329
VAL A  72
 None
 1.11A 2fb2B-3r75A:
2.1		 2fb2B-3r75A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		8 / 11 GLU A 201
GLY A 218
THR A 219
GLU A 244
HIS A 279
ARG A 352
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
PYR  A 702 ( 3.9A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.31A 2fn1A-3r75A:
43.7		 2fn1A-3r75A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		9 / 11 GLU A 201
GLY A 218
THR A 219
GLU A 244
HIS A 279
THR A 304
ARG A 352
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
BEZ  A 701 (-4.7A)
PYR  A 702 ( 3.9A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.39A 2fn1B-3r75A:
43.1		 2fn1B-3r75A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 GLY A 218
THR A 219
HIS A 279
THR A 369
ARG A 352
 BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
BEZ  A 701 (-3.8A)
BEZ  A 701 (-4.1A)
PYR  A 702 ( 3.9A)
 1.17A 2fn1B-3r75A:
43.1		 2fn1B-3r75A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 ILE A 349
THR A 314
THR A 306
VAL A 305
ARG A  80
 None
None
None
PYR  A 702 ( 4.7A)
None
 1.03A 2fr3A-3r75A:
undetectable		 2fr3A-3r75A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 6 LEU A 175
VAL A  70
MET A  71
ILE A 188
 None
 0.98A 2hyyC-3r75A:
undetectable		 2hyyC-3r75A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 6 LEU A 390
VAL A  70
MET A  71
ILE A 188
 None
 1.06A 2hyyC-3r75A:
undetectable		 2hyyC-3r75A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 THR A 199
ALA A 198
LEU A 390
LEU A 175
ILE A  37
 None
 1.12A 2jfaA-3r75A:
undetectable		 2jfaA-3r75A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.78A 2nmzA-3r75A:
undetectable		 2nmzA-3r75A:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.80A 2nnkA-3r75A:
undetectable		 2nnkA-3r75A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 5 SER A 528
GLY A 491
HIS A 514
ASP A 481
 None
 0.88A 2oxtB-3r75A:
2.9		 2oxtB-3r75A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 5 VAL A 488
TYR A 485
VAL A 480
ASP A 481
 None
 0.86A 2x45A-3r75A:
undetectable		 2x45A-3r75A:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 5 VAL A 488
TYR A 485
VAL A 480
ASP A 481
 None
 0.90A 2x45C-3r75A:
undetectable		 2x45C-3r75A:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 PRO A 497
LEU A 540
ILE A 535
VAL A 586
LEU A 600
 None
 1.26A 3a51B-3r75A:
undetectable		 3a51B-3r75A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 9 VAL A 580
GLY A 584
PRO A 603
THR A 604
GLY A 519
 None
 1.29A 3bjwG-3r75A:
undetectable		 3bjwG-3r75A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 HIS A 455
GLY A 493
ASP A 451
ILE A 505
VAL A 476
 None
CYG  A 526 ( 3.9A)
None
None
None
 1.00A 3bwcB-3r75A:
undetectable		 3bwcB-3r75A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.75A 3k4vA-3r75A:
undetectable		 3k4vA-3r75A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.79A 3k4vD-3r75A:
undetectable		 3k4vD-3r75A:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 GLY A 620
PHE A 610
GLY A 564
PHE A 565
 None
 0.77A 3ko0M-3r75A:
undetectable
3ko0P-3r75A:
undetectable		 3ko0M-3r75A:
9.91
3ko0P-3r75A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 ASP A 238
GLU A 379
ASP A 375
LEU A 370
ILE A 138
 None
MG  A 700 ( 4.5A)
None
None
None
 1.50A 3ko0K-3r75A:
undetectable
3ko0L-3r75A:
undetectable
3ko0M-3r75A:
undetectable
3ko0N-3r75A:
undetectable		 3ko0K-3r75A:
9.91
3ko0L-3r75A:
9.91
3ko0M-3r75A:
9.91
3ko0N-3r75A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 8 GLY A 620
PHE A 610
GLY A 564
PHE A 565
 None
 0.87A 3ko0O-3r75A:
undetectable
3ko0Q-3r75A:
undetectable		 3ko0O-3r75A:
9.91
3ko0Q-3r75A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.68A 3ndtA-3r75A:
undetectable		 3ndtA-3r75A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.77A 3nduD-3r75A:
undetectable		 3nduD-3r75A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.78A 3pwrA-3r75A:
undetectable		 3pwrA-3r75A:
10.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		12 / 12 GLU A 201
ILE A 216
SER A 217
GLY A 218
THR A 219
GLU A 244
HIS A 279
ARG A 352
SER A 368
THR A 369
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.2A)
BEZ  A 701 (-3.2A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
PYR  A 702 ( 3.9A)
None
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.00A 3r75A-3r75A:
74.2		 3r75A-3r75A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 GLU A 201
THR A 369
GLU A 382
THR A 219
GLU A 244
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
 1.12A 3r75A-3r75A:
74.2		 3r75A-3r75A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		12 / 12 GLU A 201
ILE A 216
SER A 217
GLY A 218
THR A 219
GLU A 244
HIS A 279
ARG A 352
SER A 368
THR A 369
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.2A)
BEZ  A 701 (-3.2A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
PYR  A 702 ( 3.9A)
None
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.05A 3r75B-3r75A:
71.0		 3r75B-3r75A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 GLU A 201
THR A 369
GLU A 382
THR A 219
GLU A 244
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
 1.10A 3r75B-3r75A:
71.0		 3r75B-3r75A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		11 / 11 GLU A 201
ILE A 216
SER A 217
GLY A 218
THR A 219
GLU A 244
HIS A 279
ARG A 352
THR A 369
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.2A)
BEZ  A 701 (-3.2A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
PYR  A 702 ( 3.9A)
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.13A 3r76A-3r75A:
71.0		 3r76A-3r75A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 GLU A 201
THR A 369
GLU A 382
THR A 219
GLU A 244
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
 1.17A 3r76A-3r75A:
71.0		 3r76A-3r75A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		11 / 11 GLU A 201
ILE A 216
SER A 217
GLY A 218
THR A 219
GLU A 244
HIS A 279
ARG A 352
THR A 369
GLU A 382
LYS A 386
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.2A)
BEZ  A 701 (-3.2A)
BEZ  A 701 (-3.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-3.8A)
PYR  A 702 ( 3.9A)
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
PYR  A 702 ( 3.1A)
 0.17A 3r76B-3r75A:
70.3		 3r76B-3r75A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 11 GLU A 201
THR A 369
GLU A 382
THR A 219
GLU A 244
 BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.1A)
MG  A 700 ( 2.5A)
BEZ  A 701 (-4.0A)
MG  A 700 ( 2.5A)
 1.19A 3r76B-3r75A:
70.3		 3r76B-3r75A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 9 ILE A  24
ALA A  22
PHE A  21
PHE A  40
LYS A  34
 None
 1.25A 3ti1A-3r75A:
undetectable		 3ti1A-3r75A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 ARG A 504
VAL A 473
THR A 457
 None
 0.75A 3tl9A-3r75A:
undetectable		 3tl9A-3r75A:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		3 / 3 THR A 369
VAL A 371
GLU A 382
 BEZ  A 701 (-4.1A)
None
MG  A 700 ( 2.5A)
 0.72A 3v4tA-3r75A:
undetectable
3v4tD-3r75A:
undetectable		 3v4tA-3r75A:
24.39
3v4tD-3r75A:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 5 ASP A 161
GLU A 120
GLY A 119
ASP A 115
 None
 1.09A 3w9tD-3r75A:
undetectable		 3w9tD-3r75A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 ILE A 535
ALA A 524
LEU A 536
LEU A 600
PHE A 522
 None
 0.90A 4pbhA-3r75A:
undetectable		 4pbhA-3r75A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 LEU A 204
SER A 347
ILE A 331
VAL A  72
 None
 1.21A 4tvtA-3r75A:
undetectable		 4tvtA-3r75A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_1
(PROLINE--TRNA LIGASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 4 THR A 304
GLU A 201
THR A 219
HIS A 279
 BEZ  A 701 (-4.7A)
BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.0A)
BEZ  A 701 (-3.8A)
 1.47A 4ydqA-3r75A:
3.1		 4ydqA-3r75A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_1
(AMINOACYL-TRNA
SYNTHETASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 4 THR A 304
GLU A 201
THR A 219
HIS A 279
 BEZ  A 701 (-4.7A)
BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.0A)
BEZ  A 701 (-3.8A)
 1.46A 5f9zA-3r75A:
1.5		 5f9zA-3r75A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_1
(AMINOACYL-TRNA
SYNTHETASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 4 THR A 304
GLU A 201
THR A 219
HIS A 279
 BEZ  A 701 (-4.7A)
BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.0A)
BEZ  A 701 (-3.8A)
 1.45A 5f9zB-3r75A:
undetectable		 5f9zB-3r75A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 LEU A 277
THR A 219
ILE A 216
LEU A 245
 None
BEZ  A 701 (-4.0A)
BEZ  A 701 (-4.2A)
None
 1.07A 5fxtA-3r75A:
undetectable		 5fxtA-3r75A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 6 LEU A 390
SER A 391
PHE A 394
ASP A 395
 None
 0.97A 5om3A-3r75A:
undetectable
5om3B-3r75A:
undetectable		 5om3A-3r75A:
7.31
5om3B-3r75A:
5.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 VAL A 362
ILE A 364
VAL A 196
ALA A 354
 None
 0.55A 5ospA-3r75A:
undetectable		 5ospA-3r75A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 7 VAL A 362
ILE A 364
VAL A 196
ALA A 354
 None
 0.58A 5osrA-3r75A:
undetectable		 5osrA-3r75A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 MET A 490
LEU A 600
ILE A 535
LEU A 536
LEU A 515
 None
 1.18A 5toaB-3r75A:
undetectable		 5toaB-3r75A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 12 PRO A 303
THR A 304
GLU A 201
THR A 219
HIS A 279
 None
BEZ  A 701 (-4.7A)
BEZ  A 701 ( 4.3A)
BEZ  A 701 (-4.0A)
BEZ  A 701 (-3.8A)
 1.47A 5xipB-3r75A:
undetectable		 5xipB-3r75A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 10 ARG A 352
VAL A 387
LEU A 390
SER A 391
GLY A 367
 PYR  A 702 ( 3.9A)
None
None
None
PYR  A 702 (-3.9A)
 1.21A 6eu9B-3r75A:
undetectable		 6eu9B-3r75A:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		5 / 10 ALA A 168
LEU A 169
VAL A 187
VAL A  13
ALA A  41
 None
 1.30A 6h1lA-3r75A:
undetectable		 6h1lA-3r75A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I
(Burkholderia
lata) 		4 / 6 VAL A 618
PRO A 621
ILE A 623
GLU A 626
 None
 1.24A 6h7uA-3r75A:
undetectable		 6h7uA-3r75A:
22.71