SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AO8_A_MTXA170_1
(DIHYDROFOLATE
REDUCTASE)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 ASP A  97
LEU A 122
PHE A  96
LEU A  84
ALA A  62
 None
 1.08A 1ao8A-3r79A:
undetectable		 1ao8A-3r79A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 10 ALA A  92
LEU A  84
ILE A 102
LEU A 157
PHE A 124
 None
 1.05A 3fl9E-3r79A:
undetectable		 3fl9E-3r79A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 10 ALA A  92
LEU A  84
ILE A 102
LEU A 157
PHE A 124
 None
 1.10A 3fl9F-3r79A:
undetectable		 3fl9F-3r79A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 12 LEU A 111
LEU A 122
SER A 121
GLY A 161
GLU A 160
 None
 1.06A 3g2oA-3r79A:
undetectable		 3g2oA-3r79A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		3 / 3 ARG A  52
ASP A  97
ASP A  75
 None
 0.84A 3jayA-3r79A:
undetectable		 3jayA-3r79A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 THR A 144
LEU A 191
LEU A 162
THR A 130
 None
 0.85A 4c9nA-3r79A:
undetectable		 4c9nA-3r79A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 5 ASN A 171
GLY A 173
ASP A  17
ASP A 198
 None
 1.11A 4n48B-3r79A:
undetectable		 4n48B-3r79A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 4 ASN A 171
GLY A 173
ASP A  17
ASP A 198
 None
 1.11A 4n49A-3r79A:
undetectable		 4n49A-3r79A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA601_1
(SERUM ALBUMIN)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		5 / 11 ARG A 211
VAL A 128
GLY A 138
THR A 130
LEU A 179
 None
 1.06A 4or0A-3r79A:
undetectable		 4or0A-3r79A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 LEU A 132
GLU A 143
HIS A 175
LEU A 178
 None
 1.25A 5dxeA-3r79A:
undetectable		 5dxeA-3r79A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		6 / 12 VAL A  11
ILE A  15
ALA A  16
VAL A 212
GLY A 213
ILE A 216
 None
 1.48A 5j2tC-3r79A:
undetectable		 5j2tC-3r79A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3r79 UNCHARACTERIZED
PROTEIN
(Agrobacterium
fabrum) 		4 / 8 LEU A 132
GLU A 143
HIS A 175
LEU A 178
 None
 1.25A 6cbzA-3r79A:
undetectable		 6cbzA-3r79A:
15.55