SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		5 / 10 ALA A  68
ALA A  72
LEU A  76
LEU A  86
ALA A  60
 None
 1.00A 2bxeA-3r7aA:
undetectable		 2bxeA-3r7aA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		4 / 8 TRP A 109
LEU A 135
GLY A 113
ALA A 116
 EPE  A 301 (-3.9A)
None
None
None
 0.93A 2xfsA-3r7aA:
undetectable		 2xfsA-3r7aA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		4 / 8 TRP A 109
LEU A 135
GLY A 113
ALA A 116
 EPE  A 301 (-3.9A)
None
None
None
 0.93A 2xh9A-3r7aA:
undetectable		 2xh9A-3r7aA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		5 / 12 ILE A 159
ILE A 183
LEU A 190
VAL A 174
LEU A  92
 None
 1.10A 3dzuA-3r7aA:
undetectable		 3dzuA-3r7aA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		3 / 3 ASN A  96
TRP A  32
ASP A 140
 None
 1.26A 4a7tA-3r7aA:
undetectable
4a7tF-3r7aA:
undetectable		 4a7tA-3r7aA:
22.86
4a7tF-3r7aA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		4 / 8 GLY A  31
GLN A  30
SER A  63
HIS A 179
 None
EPE  A 301 (-3.9A)
None
EPE  A 301 (-3.9A)
 0.81A 4wryA-3r7aA:
undetectable		 4wryA-3r7aA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		4 / 8 GLY A  31
GLN A  30
SER A  63
HIS A 179
 None
EPE  A 301 (-3.9A)
None
EPE  A 301 (-3.9A)
 0.91A 4wrzA-3r7aA:
undetectable		 4wrzA-3r7aA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		5 / 9 PHE A  97
ILE A 136
THR A 184
LEU A 197
LEU A 125
 None
 1.42A 4ze0A-3r7aA:
undetectable		 4ze0A-3r7aA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		5 / 12 GLY A  98
ALA A 145
ASP A 147
ILE A 133
ILE A 136
 None
 0.88A 5e5jB-3r7aA:
undetectable		 5e5jB-3r7aA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3r7a PHOSPHOGLYCERATE
MUTASE, PUTATIVE
(Bacillus
anthracis) 		5 / 12 GLY A  98
ALA A 145
ASP A 147
ILE A 133
ILE A 136
 None
 0.89A 5t8hB-3r7aA:
undetectable		 5t8hB-3r7aA:
17.72