SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 3r7s CASPASE-2 SUBUNIT
P18
(Homo
sapiens) 		4 / 5 ASP A 268
SER A 196
LEU A 201
GLY A 200
 None
 1.18A 2j2pA-3r7sA:
undetectable
2j2pB-3r7sA:
undetectable		 2j2pA-3r7sA:
21.50
2j2pB-3r7sA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3r7s CASPASE-2 SUBUNIT
P18
(Homo
sapiens) 		3 / 3 GLY A 222
ASP A 225
SER A 206
 None
 0.61A 2qhfA-3r7sA:
undetectable		 2qhfA-3r7sA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3r7s CASPASE-2 SUBUNIT
P18
(Homo
sapiens) 		4 / 6 PHE A 258
ALA A 263
THR A 267
LEU A 308
 None
 1.05A 4ejgD-3r7sA:
undetectable		 4ejgD-3r7sA:
15.55