SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 GLY A  36
GLY A  37
TYR A 134
HIS A 106
None
0.83A 1dbbH-3r7tA:
undetectable
1dbbL-3r7tA:
undetectable
1dbbH-3r7tA:
18.76
1dbbL-3r7tA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 6 PRO A 362
ASP A 278
ASP A 282
TYR A 364
None
None
PGE  A 422 ( 4.9A)
None
1.47A 1hpkA-3r7tA:
undetectable
1hpkA-3r7tA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 9 THR A 244
GLY A 218
GLY A  72
ARG A  33
GLY A  36
None
1.27A 1jhoA-3r7tA:
undetectable
1jhoA-3r7tA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 9 THR A 244
GLY A 218
GLY A  72
ARG A  33
GLY A  36
None
1.22A 1l4nA-3r7tA:
undetectable
1l4nA-3r7tA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 9 THR A 244
GLY A 218
GLY A  72
ARG A  33
GLY A  36
None
1.24A 1l5kA-3r7tA:
undetectable
1l5kA-3r7tA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 9 THR A 244
GLY A 218
GLY A  72
ARG A  33
GLY A  36
None
1.25A 1l5lA-3r7tA:
undetectable
1l5lA-3r7tA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 9 THR A 244
GLY A 218
GLY A  72
ARG A  33
GLY A  36
None
1.24A 1l5mA-3r7tA:
undetectable
1l5mA-3r7tA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 6 SER A 405
THR A 406
LEU A 331
ASP A 332
None
1.37A 1mxdA-3r7tA:
undetectable
1mxdA-3r7tA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 LYS A 263
THR A 406
TYR A 389
LEU A 331
None
1.03A 1z2bB-3r7tA:
2.4
1z2bB-3r7tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 GLY A 260
GLY A   9
ALA A 315
THR A 314
ALA A 322
None
0.96A 2gluA-3r7tA:
undetectable
2gluA-3r7tA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 GLY A 260
GLY A   9
ALA A 315
THR A 314
ALA A 322
None
1.02A 2gluB-3r7tA:
undetectable
2gluB-3r7tA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 ILE A  69
LEU A  80
VAL A  73
VAL A 145
ILE A 192
None
1.02A 2nnhA-3r7tA:
undetectable
2nnhA-3r7tA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 5 SER A 238
GLY A 243
HIS A 101
ASP A  98
None
1.07A 2oxtB-3r7tA:
undetectable
2oxtB-3r7tA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_B_CHDB1_0
(FERROCHELATASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 10 LEU A 193
LYS A 137
PRO A  57
VAL A  73
GLY A  70
None
1.41A 2qd2B-3r7tA:
1.0
2qd2B-3r7tA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 ILE A  69
LEU A  80
VAL A  73
VAL A 145
ILE A 192
None
1.02A 2vn0A-3r7tA:
undetectable
2vn0A-3r7tA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 GLY A 218
GLY A  70
GLY A 247
THR A 198
ILE A  68
None
None
None
GOL  A 425 (-4.0A)
None
0.91A 2wa2B-3r7tA:
undetectable
2wa2B-3r7tA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 HIS A 228
ASP A 225
SER A 238
ILE A 226
None
1.09A 2xadA-3r7tA:
undetectable
2xadA-3r7tA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 HIS A 228
ASP A 225
SER A 238
ILE A 226
None
1.09A 2xadB-3r7tA:
undetectable
2xadB-3r7tA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 HIS A 228
ASP A 225
SER A 238
ILE A 226
None
1.06A 2xadC-3r7tA:
undetectable
2xadC-3r7tA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 HIS A 228
ASP A 225
SER A 238
ILE A 226
None
1.10A 2xadD-3r7tA:
undetectable
2xadD-3r7tA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
3 / 3 TYR A 265
TYR A 389
ILE A 337
None
0.79A 3eteA-3r7tA:
undetectable
3eteB-3r7tA:
undetectable
3eteA-3r7tA:
21.40
3eteB-3r7tA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
3 / 3 ILE A 415
SER A 324
SER A 405
None
0.56A 3iltH-3r7tA:
undetectable
3iltH-3r7tA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_B_MOAB1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 10 SER A 238
SER A 237
MET A 223
GLY A 221
GLN A 220
None
1.22A 4af0B-3r7tA:
undetectable
4af0B-3r7tA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 6 ILE A 286
VAL A 330
LYS A 263
LEU A 331
None
1.04A 4em2A-3r7tA:
undetectable
4em2A-3r7tA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 LEU A 250
GLY A  70
SER A  97
ASN A  71
ILE A  68
None
1.12A 4o1eB-3r7tA:
undetectable
4o1eB-3r7tA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 THR A 314
VAL A 234
TYR A 313
GLY A 229
ILE A 240
None
1.25A 5b8hA-3r7tA:
undetectable
5b8hB-3r7tA:
undetectable
5b8hA-3r7tA:
21.18
5b8hB-3r7tA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 7 GLU A  83
GLY A  37
GLY A 127
ALA A  40
None
0.87A 5e26A-3r7tA:
undetectable
5e26B-3r7tA:
undetectable
5e26A-3r7tA:
21.63
5e26B-3r7tA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 7 ALA A  40
GLU A  83
GLY A  37
GLY A 127
None
0.84A 5e26A-3r7tA:
undetectable
5e26B-3r7tA:
undetectable
5e26A-3r7tA:
21.63
5e26B-3r7tA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 7 GLU A  83
GLY A  37
GLY A 127
ALA A  40
None
0.86A 5e26C-3r7tA:
undetectable
5e26D-3r7tA:
undetectable
5e26C-3r7tA:
21.63
5e26D-3r7tA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 SER A 237
GLY A  70
GLY A  72
GLY A  36
ASP A 199
None
0.97A 5ekxA-3r7tA:
undetectable
5ekxA-3r7tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 6 SER A 324
GLY A  16
MET A 326
ILE A   7
None
0.97A 5j4nA-3r7tA:
undetectable
5j4nA-3r7tA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 GLU A 254
GLY A 249
LEU A 248
THR A 201
None
0.94A 5sxqA-3r7tA:
undetectable
5sxqA-3r7tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 GLU A 254
GLY A 249
LEU A 248
THR A 201
None
0.92A 5sxtA-3r7tA:
undetectable
5sxtA-3r7tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 GLU A 254
GLY A 249
LEU A 248
THR A 201
None
0.90A 5sxtB-3r7tA:
undetectable
5sxtB-3r7tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 8 GLU A 254
GLY A 249
LEU A 248
THR A 201
None
0.95A 5syjB-3r7tA:
undetectable
5syjB-3r7tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 ASP A 282
LEU A 325
VAL A 262
TYR A 389
TYR A 364
PGE  A 422 ( 4.9A)
None
None
None
None
1.07A 5uxdB-3r7tA:
undetectable
5uxdB-3r7tA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
4 / 7 GLN A 220
GLY A 221
ILE A 240
TYR A 313
None
0.80A 5vlmC-3r7tA:
undetectable
5vlmC-3r7tA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_0
(ADENOSYLHOMOCYSTEINA
SE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 10 GLY A   9
GLY A 221
GLU A  15
ASP A  14
ILE A   7
None
None
None
CIT  A 421 ( 4.1A)
None
0.97A 6exiA-3r7tA:
undetectable
6exiA-3r7tA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_1
(ADENOSYLHOMOCYSTEINA
SE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 10 GLY A   9
GLY A 221
GLU A  15
ASP A  14
ILE A   7
None
None
None
CIT  A 421 ( 4.1A)
None
0.95A 6exiB-3r7tA:
undetectable
6exiB-3r7tA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 GLY A   9
GLY A 221
GLU A  15
ASP A  14
ILE A   7
None
None
None
CIT  A 421 ( 4.1A)
None
0.95A 6exiC-3r7tA:
undetectable
6exiD-3r7tA:
undetectable
6exiC-3r7tA:
12.71
6exiD-3r7tA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni)
5 / 12 GLY A   9
GLY A 221
GLU A  15
ASP A  14
ILE A   7
None
None
None
CIT  A 421 ( 4.1A)
None
0.97A 6exiC-3r7tA:
undetectable
6exiD-3r7tA:
undetectable
6exiC-3r7tA:
12.71
6exiD-3r7tA:
12.71