SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r8c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_D_SAMD200_0 (METHIONINE REPRESSOR)	3r8c	CYTIDYLATE KINASE (Mycobacteroides abscessus)	5 / 12	GLY A 31 ARG A 43 LEU A 76 ALA A 74 PRO A 84	None	1.04A	1mjqC-3r8cA: undetectable 1mjqD-3r8cA: undetectable	1mjqC-3r8cA: 17.65 1mjqD-3r8cA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_J_SAMJ200_0 (METHIONINE REPRESSOR)	3r8c	CYTIDYLATE KINASE (Mycobacteroides abscessus)	5 / 12	GLY A 31 ARG A 43 LEU A 76 ALA A 74 PRO A 84	None	1.04A	1mjqI-3r8cA: undetectable 1mjqJ-3r8cA: undetectable	1mjqI-3r8cA: 17.65 1mjqJ-3r8cA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_C_SPMC1434_1 (NITROALKANE OXIDASE)	3r8c	CYTIDYLATE KINASE (Mycobacteroides abscessus)	5 / 12	MET A 0 LEU A 23 VAL A 4 LEU A 19 VAL A 15	None	0.97A	2c12C-3r8cA: undetectable	2c12C-3r8cA: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OM2_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRY PSIN)	3r8c	CYTIDYLATE KINASE (Mycobacteroides abscessus)	5 / 9	VAL A 4 LEU A 19 ALA A 20 VAL A 138 ILE A 140	None	1.09A	5om2A-3r8cA: undetectable 5om2B-3r8cA: undetectable	5om2A-3r8cA: 15.62 5om2B-3r8cA: 9.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MJQ_D_SAMD200_0","METHIONINE REPRESSOR","3r8c","CYTIDYLATE KINASE","Mycobacteroides abscessus",5,"GLY A  31;ARG A  43;LEU A  76;ALA A  74;PRO A  84","None","1.04A","1mjqC-3r8cA:undetectable;1mjqD-3r8cA:undetectable","1mjqC-3r8cA:17.65;1mjqD-3r8cA:17.65"],["1MJQ_J_SAMJ200_0","METHIONINE REPRESSOR","3r8c","CYTIDYLATE KINASE","Mycobacteroides abscessus",5,"GLY A  31;ARG A  43;LEU A  76;ALA A  74;PRO A  84","None","1.04A","1mjqI-3r8cA:undetectable;1mjqJ-3r8cA:undetectable","1mjqI-3r8cA:17.65;1mjqJ-3r8cA:17.65"],["2C12_C_SPMC1434_1","NITROALKANE OXIDASE","3r8c","CYTIDYLATE KINASE","Mycobacteroides abscessus",5,"MET A   0;LEU A  23;VAL A   4;LEU A  19;VAL A  15","None","0.97A","2c12C-3r8cA:undetectable","2c12C-3r8cA:20.99"],["5OM2_B_DXTB501_1","ALPHA-1-ANTICHYMOTRYPSIN;ALPHA-1-ANTICHYMOTRYPSIN","3r8c","CYTIDYLATE KINASE","Mycobacteroides abscessus",5,"VAL A   4;LEU A  19;ALA A  20;VAL A 138;ILE A 140","None","1.09A","5om2A-3r8cA:undetectable;5om2B-3r8cA:undetectable","5om2A-3r8cA:15.62;5om2B-3r8cA:9.15"]]