SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r8y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.01A 1fb7A-3r8yA:
undetectable		 1fb7A-3r8yA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 9 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.09A 1hpvB-3r8yA:
undetectable		 1hpvB-3r8yA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.07A 1hsgB-3r8yA:
undetectable		 1hsgB-3r8yA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 0.99A 1sdtB-3r8yA:
undetectable		 1sdtB-3r8yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.11A 1sduB-3r8yA:
undetectable		 1sduB-3r8yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		3 / 3 LYS A 164
ASP A 170
CYH A 146
 None
 1.30A 2br4F-3r8yA:
undetectable		 2br4F-3r8yA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.00A 2hs2B-3r8yA:
undetectable		 2hs2B-3r8yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 0.86A 3jw2A-3r8yA:
undetectable		 3jw2A-3r8yA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		4 / 7 GLU A 200
VAL A 184
VAL A 208
ALA A 213
 None
 1.00A 3kp6B-3r8yA:
undetectable		 3kp6B-3r8yA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.11A 3mwsB-3r8yA:
undetectable		 3mwsB-3r8yA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.04A 3ndxA-3r8yA:
undetectable		 3ndxA-3r8yA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 10 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.01A 3nu6B-3r8yA:
undetectable		 3nu6B-3r8yA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 9 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 1.08A 4ll3B-3r8yA:
undetectable		 4ll3B-3r8yA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 VAL A 104
ALA A 140
PRO A  83
ALA A 122
GLY A 121
 None
 0.95A 5tzoA-3r8yA:
undetectable		 5tzoA-3r8yA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 3r8y 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-ACETYLTRANSFERASE
(Bacillus
anthracis) 		5 / 12 ALA A  92
ASP A 108
GLY A  89
VAL A 104
ILE A 106
 None
 0.92A 6difA-3r8yA:
undetectable		 6difA-3r8yA:
17.50