SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r95'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 3r95 MCCE PROTEIN
(Escherichia
coli) 		5 / 11 PHE A 137
ILE A 121
ASN A 119
GLY A 156
PHE A 157
 None
None
ACO  A 601 ( 4.4A)
None
None
 1.27A 1hvyC-3r95A:
undetectable		 1hvyC-3r95A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 3r95 MCCE PROTEIN
(Escherichia
coli) 		4 / 7 ALA A 150
SER A 148
VAL A 117
ARG A 154
 None
ACO  A 601 (-3.2A)
ACO  A 601 (-3.8A)
ACO  A 601 (-3.5A)
 1.00A 4ijiH-3r95A:
undetectable		 4ijiH-3r95A:
22.37