SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 PHE A  35
LEU A  78
ALA A  74
ALA A  70
LEU A  49
 None
 1.26A 1cbrA-3r97A:
undetectable		 1cbrA-3r97A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 PHE A  35
LEU A  78
ALA A  74
ALA A  70
LEU A  58
 None
 1.02A 1cbrA-3r97A:
undetectable		 1cbrA-3r97A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 PHE A  35
LEU A  78
ALA A  74
ALA A  70
LEU A  49
 None
 1.26A 1cbrB-3r97A:
undetectable		 1cbrB-3r97A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 PHE A  35
LEU A  78
ALA A  74
ALA A  70
LEU A  58
 None
 1.02A 1cbrB-3r97A:
undetectable		 1cbrB-3r97A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 ARG A  86
GLY A  84
LEU A  78
VAL A  75
ALA A 275
 None
 1.11A 1gseA-3r97A:
undetectable		 1gseA-3r97A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 ARG A  86
GLY A  84
LEU A  78
VAL A  75
ALA A 275
 None
 1.02A 1gseB-3r97A:
undetectable		 1gseB-3r97A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 ALA A  71
VAL A  73
TRP A  76
 None
 0.91A 1tkqB-3r97A:
undetectable		 1tkqB-3r97A:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 ALA A  38
GLN A  30
LEU A  24
LEU A  46
SER A  50
 None
 1.38A 2nv4B-3r97A:
undetectable		 2nv4B-3r97A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 LEU A  58
ASN A  59
LEU A  95
ARG A 119
MET A  20
 None
 1.35A 2oaxA-3r97A:
undetectable		 2oaxA-3r97A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		5 / 12 LEU A  58
ASN A  59
LEU A  95
ARG A 119
MET A  20
 None
 1.26A 2oaxC-3r97A:
undetectable		 2oaxC-3r97A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 LEU A  21
TRP A  76
TYR A 305
 None
 0.76A 3aicA-3r97A:
undetectable		 3aicA-3r97A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 LEU A  21
TRP A  76
TYR A 305
 None
 0.77A 3aicB-3r97A:
undetectable		 3aicB-3r97A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 LEU A  21
TRP A  76
TYR A 305
 None
 0.79A 3aicE-3r97A:
undetectable		 3aicE-3r97A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 LEU A  21
TRP A  76
TYR A 305
 None
 0.84A 3aicF-3r97A:
undetectable		 3aicF-3r97A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 LEU A  21
TRP A  76
TYR A 305
 None
 0.78A 3aicG-3r97A:
undetectable		 3aicG-3r97A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 LEU A  21
TRP A  76
TYR A 305
 None
 0.80A 3aicH-3r97A:
undetectable		 3aicH-3r97A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		3 / 3 MET A 123
VAL A 198
GLU A  62
 None
 0.84A 3c6gA-3r97A:
undetectable		 3c6gA-3r97A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		4 / 8 GLY A 173
ALA A 127
HIS A 203
THR A 204
 None
None
NHE  A 315 (-4.1A)
None
 0.93A 5eevL-3r97A:
undetectable
5eevV-3r97A:
undetectable		 5eevL-3r97A:
13.84
5eevV-3r97A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		4 / 8 GLY A 173
ALA A 127
HIS A 203
THR A 204
 None
None
NHE  A 315 (-4.1A)
None
 0.93A 5eewL-3r97A:
undetectable
5eewV-3r97A:
undetectable		 5eewL-3r97A:
13.84
5eewV-3r97A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		4 / 8 GLY A 173
ALA A 127
HIS A 203
THR A 204
 None
None
NHE  A 315 (-4.1A)
None
 0.93A 5ef3L-3r97A:
undetectable
5ef3V-3r97A:
undetectable		 5ef3L-3r97A:
13.84
5ef3V-3r97A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3r97 MALONYL COA-ACP
TRANSACYLASE
(Xanthomonas
oryzae) 		4 / 8 LEU A 294
ILE A 271
ALA A   7
PRO A 166
 None
 0.92A 5m0oC-3r97A:
undetectable		 5m0oC-3r97A:
22.19