SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 12 GLY A 236
ALA A 233
ALA A 240
ILE A 228
GLN A  29
 None
 1.18A 1nt2A-3r9jA:
2.7		 1nt2A-3r9jA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 4 ASP A  47
ASP A  59
ASP A 120
GLY A  42
 None
 1.09A 2igtC-3r9jA:
2.1		 2igtC-3r9jA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 9 GLY A  10
LEU A 157
SER A 153
LEU A 203
ASP A 152
 None
 1.48A 2j2pB-3r9jA:
undetectable
2j2pC-3r9jA:
undetectable		 2j2pB-3r9jA:
21.25
2j2pC-3r9jA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 6 THR A   8
ASP A 120
THR A  17
ASP A  47
 None
None
ADP  A 261 (-3.5A)
None
 1.07A 2okcB-3r9jA:
undetectable		 2okcB-3r9jA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 7 ALA A  24
THR A  25
ALA A  28
PRO A 226
 None
 0.85A 2ql8A-3r9jA:
undetectable
2ql8B-3r9jA:
undetectable		 2ql8A-3r9jA:
19.92
2ql8B-3r9jA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 10 GLU A 244
GLY A 236
VAL A 217
LEU A 179
THR A  18
 None
None
ADP  A 261 (-4.4A)
None
ADP  A 261 (-3.8A)
 1.38A 3a3yA-3r9jA:
3.2		 3a3yA-3r9jA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 11 ASP A 230
ALA A 233
ASP A 234
ILE A 211
LEU A 218
 None
None
None
ADP  A 261 (-4.6A)
None
 0.94A 3em4U-3r9jA:
undetectable		 3em4U-3r9jA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 12 ILE A 211
ARG A 251
SER A  19
ILE A  23
LEU A 246
 ADP  A 261 (-4.6A)
None
None
None
None
 1.09A 3k2hB-3r9jA:
3.9		 3k2hB-3r9jA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 8 THR A 242
LEU A 179
VAL A 227
VAL A 217
 None
None
None
ADP  A 261 (-4.4A)
 1.07A 4l4bA-3r9jA:
undetectable		 4l4bA-3r9jA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 4 VAL A 227
ALA A 220
ASN A 222
GLN A 223
 None
 1.45A 4zgfA-3r9jA:
undetectable		 4zgfA-3r9jA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 6 GLU A 225
GLY A  13
ARG A 182
GLY A  15
 None
ADP  A 261 (-3.4A)
ADP  A 261 (-3.5A)
ADP  A 261 (-3.2A)
 0.84A 5cdnA-3r9jA:
undetectable
5cdnB-3r9jA:
3.2		 5cdnA-3r9jA:
21.58
5cdnB-3r9jA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 7 SER A  19
ALA A  22
GLY A 236
VAL A 227
 None
 0.85A 5fpdB-3r9jA:
undetectable		 5fpdB-3r9jA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		4 / 4 THR A 242
LEU A 246
HIS A 177
GLY A 248
 None
 0.99A 5gwyA-3r9jA:
undetectable		 5gwyA-3r9jA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3r9j SEPTUM
SITE-DETERMINING
PROTEIN MIND
(Escherichia
coli) 		5 / 12 VAL A 227
ALA A 233
SER A 216
ARG A 251
PRO A 212
 None
 1.39A 5hnzB-3r9jA:
5.4		 5hnzB-3r9jA:
20.35