SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3r9l NUCLEOSIDE
DIPHOSPHATE KINASE
(Giardia
intestinalis) 		5 / 12 THR A   6
GLY A 118
SER A 119
VAL A  10
ILE A 115
 None
 0.94A 2b25B-3r9lA:
undetectable		 2b25B-3r9lA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 3r9l NUCLEOSIDE
DIPHOSPHATE KINASE
(Giardia
intestinalis) 		5 / 9 ARG A 104
GLY A 105
ILE A 116
THR A   6
VAL A  82
 None
 1.22A 2nnhB-3r9lA:
undetectable		 2nnhB-3r9lA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3r9l NUCLEOSIDE
DIPHOSPHATE KINASE
(Giardia
intestinalis) 		3 / 3 THR A  93
VAL A 111
GLU A  97
 None
 0.55A 3v4tA-3r9lA:
undetectable
3v4tD-3r9lA:
undetectable		 3v4tA-3r9lA:
17.97
3v4tD-3r9lA:
17.97