SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 LEU A 117
MET A  89
LEU A 141
CYH A  65
THR A  63
 None
 1.44A 2oaxA-3r9qA:
undetectable		 2oaxA-3r9qA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		3 / 3 LEU A 152
ARG A 151
ILE A 153
 None
 0.60A 2xn5B-3r9qA:
undetectable		 2xn5B-3r9qA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 6 LEU A  57
VAL A  20
LEU A  96
ASP A  49
 None
 0.84A 3cs9D-3r9qA:
undetectable		 3cs9D-3r9qA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 5 LEU A 117
ARG A 122
ILE A 176
ARG A 157
 None
 1.40A 3ticA-3r9qA:
undetectable		 3ticA-3r9qA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 11 LEU A 115
ALA A 116
LEU A  22
GLY A 106
HIS A 107
 None
 1.23A 5dxgB-3r9qA:
undetectable		 5dxgB-3r9qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 TRP A 118
PHE A  43
ALA A  55
GLY A  59
LEU A 115
 None
 1.09A 5m24A-3r9qA:
undetectable		 5m24A-3r9qA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 LEU A 149
ILE A 147
ILE A 153
GLY A 154
LEU A 117
 None
None
None
CL  A 259 (-3.2A)
None
 0.98A 5twjA-3r9qA:
undetectable		 5twjA-3r9qA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 ALA A 192
ARG A 208
VAL A 100
ASP A  49
PHE A  46
 None
 1.42A 5vlmD-3r9qA:
undetectable		 5vlmD-3r9qA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3r9q ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 CYH A  65
ALA A 110
GLY A 131
LEU A  39
LEU A  22
 None
 1.17A 5wwsA-3r9qA:
undetectable		 5wwsA-3r9qA:
20.39