SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3r9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 PHE A  29
LEU A  70
SER A  57
 PHE  A  29 ( 1.3A)
LEU  A  70 ( 0.6A)
SER  A  57 ( 0.0A)
 0.81A 1e7aA-3r9rA:
undetectable		 1e7aA-3r9rA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 ASP A  48
PHE A 289
ARG A  51
 ASP  A  48 ( 0.6A)
PHE  A 289 ( 1.3A)
ARG  A  51 ( 0.6A)
 0.85A 2a3aA-3r9rA:
undetectable		 2a3aA-3r9rA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		4 / 5 PHE A 201
PHE A 199
PHE A 216
VAL A  66
 PHE  A 201 ( 1.3A)
PHE  A 199 ( 1.3A)
PHE  A 216 ( 1.3A)
VAL  A  66 ( 0.6A)
 1.16A 2lh6A-3r9rA:
undetectable		 2lh6A-3r9rA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		4 / 4 LEU A 125
PRO A 126
LEU A 129
ARG A 134
 LEU  A 125 ( 0.6A)
PRO  A 126 ( 1.1A)
LEU  A 129 ( 0.6A)
ARG  A 134 ( 0.6A)
 1.18A 3hcoB-3r9rA:
undetectable		 3hcoB-3r9rA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 ASN A 154
ASP A 152
ARG A 244
 ASN  A 154 ( 0.6A)
ASP  A 152 ( 0.6A)
ARG  A 244 ( 0.6A)
 0.83A 3k13A-3r9rA:
undetectable		 3k13A-3r9rA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		4 / 5 ILE A  46
ILE A 278
TYR A 277
GLU A 279
 ILE  A  46 ( 0.7A)
ILE  A 278 ( 0.7A)
TYR  A 277 ( 1.3A)
GLU  A 279 ( 0.6A)
 1.23A 4a99D-3r9rA:
undetectable		 4a99D-3r9rA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		4 / 6 PHE A 289
ALA A  55
GLY A 294
PRO A 295
 PHE  A 289 ( 1.3A)
ALA  A  55 ( 0.0A)
GLY  A 294 ( 0.0A)
PRO  A 295 ( 1.1A)
 0.87A 4dubB-3r9rA:
undetectable		 4dubB-3r9rA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 GLY A 253
SER A 252
TRP A 246
 GLY  A 253 ( 0.0A)
SER  A 252 ( 0.0A)
TRP  A 246 ( 0.5A)
 0.97A 4e7cD-3r9rA:
undetectable		 4e7cD-3r9rA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		4 / 4 ARG A  34
HIS A  10
ALA A  12
GLU A  18
 ARG  A  34 ( 0.6A)
HIS  A  10 ( 1.0A)
ALA  A  12 ( 0.0A)
GLU  A  18 ( 0.5A)
 1.34A 5a06A-3r9rA:
0.0
5a06F-3r9rA:
0.0		 5a06A-3r9rA:
22.82
5a06F-3r9rA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 THR A 181
PRO A 138
ASP A 136
 THR  A 181 ( 0.8A)
PRO  A 138 ( 1.1A)
ASP  A 136 ( 0.6A)
 0.91A 5l8dB-3r9rA:
undetectable		 5l8dB-3r9rA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 THR A 181
PRO A 138
ASP A 136
 THR  A 181 ( 0.8A)
PRO  A 138 ( 1.1A)
ASP  A 136 ( 0.6A)
 0.91A 5mwuB-3r9rA:
undetectable		 5mwuB-3r9rA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 TYR A 105
SER A 133
TRP A 224
 TYR  A 105 ( 1.3A)
SER  A 133 ( 0.0A)
TRP  A 224 ( 0.5A)
 0.80A 5n8jB-3r9rA:
undetectable		 5n8jB-3r9rA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 TYR A 105
SER A 133
TRP A 224
 TYR  A 105 ( 1.3A)
SER  A 133 ( 0.0A)
TRP  A 224 ( 0.5A)
 0.81A 5n8jA-3r9rA:
undetectable		 5n8jA-3r9rA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 TYR A 105
SER A 133
TRP A 224
 TYR  A 105 ( 1.3A)
SER  A 133 ( 0.0A)
TRP  A 224 ( 0.5A)
 0.85A 5n8jD-3r9rA:
undetectable		 5n8jD-3r9rA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		4 / 8 THR A 181
TYR A 180
THR A 176
ARG A 173
 THR  A 181 ( 0.8A)
TYR  A 180 ( 1.3A)
THR  A 176 ( 0.8A)
ARG  A 173 ( 0.6A)
 1.40A 5tzoA-3r9rA:
undetectable		 5tzoA-3r9rA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		4 / 5 LEU A  28
VAL A  83
GLU A  82
LEU A   5
 LEU  A  28 ( 0.6A)
VAL  A  83 ( 0.6A)
GLU  A  82 ( 0.5A)
LEU  A   5 ( 0.6A)
 0.93A 5xooB-3r9rA:
3.0		 5xooB-3r9rA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A 202
GLY A 207
ASP A 213
ASP A  94
MET A  95
 GLY  A 202 ( 0.0A)
GLY  A 207 ( 0.0A)
ASP  A 213 ( 0.6A)
ASP  A  94 ( 0.6A)
MET  A  95 ( 0.0A)
 1.36A 5yn6A-3r9rA:
undetectable		 5yn6A-3r9rA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A  -1
SER A   4
ALA A  87
ARG A  86
PRO A 295
 GLY  A  -1 ( 0.0A)
SER  A   4 ( 0.0A)
ALA  A  87 ( 0.0A)
ARG  A  86 ( 0.6A)
PRO  A 295 ( 1.1A)
 1.07A 5zvgA-3r9rA:
undetectable		 5zvgA-3r9rA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A  -1
SER A   4
ALA A  87
ARG A  86
PRO A 295
 GLY  A  -1 ( 0.0A)
SER  A   4 ( 0.0A)
ALA  A  87 ( 0.0A)
ARG  A  86 ( 0.6A)
PRO  A 295 ( 1.1A)
 1.05A 5zvgB-3r9rA:
undetectable		 5zvgB-3r9rA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE
(Mycobacteroides
abscessus) 		3 / 3 ILE A 177
THR A 176
PRO A 138
 ILE  A 177 ( 0.7A)
THR  A 176 ( 0.8A)
PRO  A 138 ( 1.1A)
 0.65A 6ncsA-3r9rA:
undetectable		 6ncsA-3r9rA:
19.63