SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ra2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.24A 1p6kA-3ra2A:
undetectable
1p6kA-3ra2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.24A 1p6kB-3ra2A:
undetectable
1p6kB-3ra2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.24A 1rs6A-3ra2A:
undetectable
1rs6A-3ra2A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.26A 1rs6B-3ra2A:
undetectable
1rs6B-3ra2A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.23A 1rs7B-3ra2A:
undetectable
1rs7B-3ra2A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.87A 1v54N-3ra2A:
undetectable
1v54W-3ra2A:
undetectable
1v54N-3ra2A:
23.22
1v54W-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.94A 1v55A-3ra2A:
undetectable
1v55J-3ra2A:
undetectable
1v55A-3ra2A:
23.22
1v55J-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
5 / 10 GLY A 639
THR A 731
VAL A 614
GLU A 565
SER A 634
None
1.20A 1z35A-3ra2A:
undetectable
1z35A-3ra2A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.23A 1zzqA-3ra2A:
undetectable
1zzqA-3ra2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.24A 1zzqB-3ra2A:
undetectable
1zzqB-3ra2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.22A 1zzuA-3ra2A:
undetectable
1zzuA-3ra2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.24A 1zzuB-3ra2A:
undetectable
1zzuB-3ra2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.85A 2dyrN-3ra2A:
undetectable
2dyrW-3ra2A:
undetectable
2dyrN-3ra2A:
23.22
2dyrW-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
3 / 3 TRP A 282
GLN A 648
TRP A 248
None
1.36A 2vqyA-3ra2A:
undetectable
2vqyA-3ra2A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
3 / 3 TYR A 733
GLU A 567
THR A 563
None
1.04A 2y7hB-3ra2A:
undetectable
2y7hB-3ra2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.93A 3ablN-3ra2A:
undetectable
3ablW-3ra2A:
undetectable
3ablN-3ra2A:
23.22
3ablW-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.90A 3ag3A-3ra2A:
undetectable
3ag3J-3ra2A:
undetectable
3ag3A-3ra2A:
23.22
3ag3J-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.89A 3asnN-3ra2A:
undetectable
3asnW-3ra2A:
undetectable
3asnN-3ra2A:
23.22
3asnW-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 SER A 393
ASN A 384
GLN A 388
PHE A 276
None
1.27A 3n62B-3ra2A:
undetectable
3n62B-3ra2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 5 PHE A 294
LEU A 689
GLY A 308
VAL A 614
None
1.06A 3wrkD-3ra2A:
undetectable
3wrkD-3ra2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
3 / 3 TYR A 427
HIS A 429
ARG A 736
None
1.07A 4e7bC-3ra2A:
undetectable
4e7bC-3ra2A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 6 LEU A 353
TYR A 355
LEU A 650
TYR A 378
None
1.15A 4f3tA-3ra2A:
undetectable
4f3tA-3ra2A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
5 / 12 LEU A 357
GLN A 648
VAL A 356
GLY A 363
THR A 280
None
0.94A 4m2vA-3ra2A:
undetectable
4m2vA-3ra2A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 6 TYR A 258
ASN A 254
GLU A 399
TYR A 380
None
1.43A 4twdG-3ra2A:
undetectable
4twdH-3ra2A:
undetectable
4twdG-3ra2A:
22.15
4twdH-3ra2A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U3E_A_ACTA705_0
(RIBONUCLEOSIDE
TRIPHOSPHATE
REDUCTASE)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 4 HIS A 361
ASP A 286
TYR A 284
VAL A 356
None
1.42A 4u3eA-3ra2A:
0.0
4u3eA-3ra2A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.36A 4v2yA-3ra2A:
undetectable
4v2yA-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.37A 4v2yB-3ra2A:
undetectable
4v2yB-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.39A 4v2zA-3ra2A:
undetectable
4v2zA-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.34A 4v2zB-3ra2A:
undetectable
4v2zB-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.38A 4v30A-3ra2A:
undetectable
4v30A-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.26A 4v30B-3ra2A:
undetectable
4v30B-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 6 LEU A 353
TYR A 355
PRO A 354
TYR A 378
None
1.31A 4z4gA-3ra2A:
undetectable
4z4gA-3ra2A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 HIS A 230
LYS A 317
GLY A 227
ASN A 228
None
1.29A 5a5zC-3ra2A:
undetectable
5a5zC-3ra2A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.44A 5amhA-3ra2A:
undetectable
5amhA-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.37A 5amiA-3ra2A:
undetectable
5amiA-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.39A 5amiB-3ra2A:
undetectable
5amiB-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.38A 5amjA-3ra2A:
undetectable
5amjA-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.35A 5amjB-3ra2A:
undetectable
5amjB-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.32A 5amkB-3ra2A:
undetectable
5amkB-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 SER A 426
ASP A 238
ARG A 239
GLU A 686
None
1.09A 5btfA-3ra2A:
undetectable
5btfC-3ra2A:
undetectable
5btfD-3ra2A:
undetectable
5btfA-3ra2A:
20.95
5btfC-3ra2A:
20.95
5btfD-3ra2A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.38A 5oh1A-3ra2A:
undetectable
5oh1A-3ra2A:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.33A 5oh1B-3ra2A:
undetectable
5oh1B-3ra2A:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.38A 5oh3A-3ra2A:
undetectable
5oh3A-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 PRO A 311
PHE A 640
TRP A 621
TYR A 355
None
1.36A 5oh3B-3ra2A:
undetectable
5oh3B-3ra2A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.78A 5xdqN-3ra2A:
undetectable
5xdqW-3ra2A:
undetectable
5xdqN-3ra2A:
23.22
5xdqW-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.92A 5xdxA-3ra2A:
undetectable
5xdxJ-3ra2A:
undetectable
5xdxA-3ra2A:
23.22
5xdxJ-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 8 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.77A 5xdxN-3ra2A:
undetectable
5xdxW-3ra2A:
undetectable
5xdxN-3ra2A:
23.22
5xdxW-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
5 / 12 GLY A 618
GLY A 639
ALA A 622
PHE A 418
PHE A 309
None
0.98A 6nj9K-3ra2A:
undetectable
6nj9K-3ra2A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.90A 6nmfA-3ra2A:
undetectable
6nmfJ-3ra2A:
undetectable
6nmfA-3ra2A:
23.22
6nmfJ-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 7 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.95A 6nmpA-3ra2A:
undetectable
6nmpJ-3ra2A:
undetectable
6nmpA-3ra2A:
23.22
6nmpJ-3ra2A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3ra2 CAPSID PROTEIN
(Adeno-associated
dependoparvoviru
s
A)
4 / 5 ILE A 375
LEU A 250
ARG A 246
LEU A 318
None
0.85A 6nmpN-3ra2A:
undetectable
6nmpW-3ra2A:
undetectable
6nmpN-3ra2A:
23.22
6nmpW-3ra2A:
9.24