SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ra7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 3ra7 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 128
PRO H 130
THR H 129
PRO H 159
 None
 1.28A 1dsdC-3ra7H:
undetectable		 1dsdC-3ra7H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 3ra7 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 129
PRO H 159
THR H 128
PRO H 130
 None
 1.21A 1dsdC-3ra7H:
undetectable		 1dsdC-3ra7H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 3ra7 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 128
PRO H 130
THR H 129
PRO H 159
 None
 1.28A 1dsdC-3ra7H:
undetectable		 1dsdC-3ra7H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 3ra7 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR H 129
PRO H 159
THR H 128
PRO H 130
 None
 1.21A 1dsdC-3ra7H:
undetectable		 1dsdC-3ra7H:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3ra7 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 VAL H 175
VAL H 193
SER H 191
ASN H 208
ASN H 167
 None
 1.49A 2y03B-3ra7H:
undetectable		 2y03B-3ra7H:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 3ra7 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		5 / 12 VAL H 175
VAL H 193
SER H 191
ASN H 208
ASN H 167
 None
 1.41A 3nyaA-3ra7H:
undetectable		 3nyaA-3ra7H:
19.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 3ra7 FAB FRAGMENT, HEAVY
CHAIN
(Mus
musculus) 		5 / 5 SER H 124
ALA H 126
PHE H 158
LEU H 182
ASP H 185
 None
 0.80A 5mthA-3ra7H:
25.1		 5mthA-3ra7H:
69.91