SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 11 LEU A  45
VAL A 202
VAL A 114
TYR A 182
GLY A 184
 None
 1.40A 1fkpA-3raoA:
undetectable		 1fkpA-3raoA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 9 LEU A  45
VAL A 202
VAL A 114
TYR A 182
GLY A 184
 None
 1.40A 1lwfA-3raoA:
undetectable		 1lwfA-3raoA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 GLU A 278
ASN A 296
TRP A 252
 None
 1.23A 1r15C-3raoA:
undetectable		 1r15C-3raoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 GLU A 278
ASN A 296
TRP A 252
 None
 1.21A 1r15D-3raoA:
undetectable		 1r15D-3raoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 GLU A 278
ASN A 296
TRP A 252
 None
 1.21A 1r15E-3raoA:
undetectable		 1r15E-3raoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 GLU A 278
ASN A 296
TRP A 252
 None
 1.19A 1r15F-3raoA:
undetectable		 1r15F-3raoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 6 ARG A 108
SER A 105
ILE A 101
ALA A  68
ALA A  33
 None
 1.41A 1w0gA-3raoA:
undetectable		 1w0gA-3raoA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 TRP A  13
VAL A 239
TRP A   6
 None
None
SO4  A 353 (-4.8A)
 1.31A 2xdcC-3raoA:
undetectable
2xdcD-3raoA:
undetectable		 2xdcC-3raoA:
2.96
2xdcD-3raoA:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 TRP A  13
VAL A 239
TRP A   6
 None
None
SO4  A 353 (-4.8A)
 1.28A 2xdcE-3raoA:
undetectable
2xdcF-3raoA:
undetectable		 2xdcE-3raoA:
2.96
2xdcF-3raoA:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 TRP A  13
VAL A 239
TRP A   6
 None
None
SO4  A 353 (-4.8A)
 1.31A 2y5mE-3raoA:
undetectable
2y5mF-3raoA:
undetectable		 2y5mE-3raoA:
2.96
2y5mF-3raoA:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 TRP A  13
VAL A 239
TRP A   6
 None
None
SO4  A 353 (-4.8A)
 1.32A 2y6nC-3raoA:
undetectable
2y6nD-3raoA:
undetectable		 2y6nC-3raoA:
2.96
2y6nD-3raoA:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 TRP A  13
VAL A 239
TRP A   6
 None
None
SO4  A 353 (-4.8A)
 1.32A 2y6nE-3raoA:
undetectable
2y6nF-3raoA:
undetectable		 2y6nE-3raoA:
2.96
2y6nF-3raoA:
2.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 THR A  43
SER A  42
PHE A 333
 None
 0.89A 3d4sA-3raoA:
undetectable		 3d4sA-3raoA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 12 PHE A   5
ALA A  68
ALA A  29
GLU A  37
THR A 110
 None
 1.27A 3dl9B-3raoA:
undetectable		 3dl9B-3raoA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 12 GLY A 299
GLN A 303
ILE A 308
VAL A 337
LEU A 340
 None
SO4  A 354 (-4.6A)
None
None
None
 1.10A 4fr0A-3raoA:
undetectable		 4fr0A-3raoA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 12 LEU A 249
GLY A 299
GLN A 303
GLN A 280
THR A 256
 None
None
SO4  A 354 (-4.6A)
None
None
 1.24A 4p6xI-3raoA:
undetectable		 4p6xI-3raoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 10 MET A  81
LEU A  45
LEU A 321
GLY A 234
LEU A 318
 None
 1.38A 5dxbA-3raoA:
undetectable		 5dxbA-3raoA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_1
(AMINOACYL-TRNA
SYNTHETASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		4 / 4 THR A  66
GLU A  63
THR A  94
HIS A  89
 None
 1.22A 5f9zA-3raoA:
undetectable		 5f9zA-3raoA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_1
(AMINOACYL-TRNA
SYNTHETASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		4 / 4 THR A  66
GLU A  63
THR A  94
HIS A  89
 None
 1.20A 5f9zB-3raoA:
0.8		 5f9zB-3raoA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		5 / 12 GLY A 205
GLY A 292
SER A 289
VAL A 211
LEU A 235
 None
None
SO4  A 353 ( 3.2A)
None
None
 1.18A 5kocB-3raoA:
undetectable		 5kocB-3raoA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3rao PUTATIVE
LUCIFERASE-LIKE
MONOOXYGENASE
(Bacillus
cereus) 		3 / 3 LYS A 172
PRO A 171
LYS A  96
 None
 1.31A 5y9yA-3raoA:
undetectable		 5y9yA-3raoA:
21.66