SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3raz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3raz THIOREDOXIN-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 7 ILE A  45
THR A 126
MET A  77
TRP A  66
 None
 1.21A 1kglA-3razA:
undetectable		 1kglA-3razA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 3raz THIOREDOXIN-RELATED
PROTEIN
(Neisseria
meningitidis) 		3 / 3 TYR A 135
MET A  77
LEU A 148
 None
 0.89A 3vw1D-3razA:
undetectable		 3vw1D-3razA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3raz THIOREDOXIN-RELATED
PROTEIN
(Neisseria
meningitidis) 		4 / 8 GLY A  79
THR A 126
LEU A 123
ASN A  47
 None
 1.19A 4m5mA-3razA:
undetectable		 4m5mA-3razA:
20.00