SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rbn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3rbn DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		4 / 4 LEU A 148
VAL A 145
ILE A 144
TRP A 199
 None
 1.36A 1s9qB-3rbnA:
undetectable		 1s9qB-3rbnA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3rbn DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		5 / 10 LEU A  97
LEU A 209
GLU A 162
LEU A 155
MET A 154
 None
 1.23A 1wopA-3rbnA:
undetectable		 1wopA-3rbnA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 3rbn DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		3 / 3 SER A 210
HIS A 260
ASP A 177
 None
 0.77A 2wa2B-3rbnA:
undetectable		 2wa2B-3rbnA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3rbn DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		4 / 8 LEU A 186
PHE A 216
VAL A 180
LEU A 107
 None
 0.88A 3uniB-3rbnA:
undetectable		 3uniB-3rbnA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3rbn DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		3 / 3 LEU A 172
PRO A 173
ARG A 220
 None
 0.74A 4klrB-3rbnA:
undetectable		 4klrB-3rbnA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3rbn DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		4 / 8 LEU A  92
TYR A 179
VAL A 253
ILE A 219
 None
 0.94A 5v0vA-3rbnA:
undetectable		 5v0vA-3rbnA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3rbn DNA MISMATCH REPAIR
PROTEIN MLH1
(Homo
sapiens) 		4 / 6 GLN A  43
PHE A 101
PHE A 104
LEU A 175
 None
 1.11A 5z86C-3rbnA:
undetectable
5z86J-3rbnA:
undetectable		 5z86C-3rbnA:
20.53
5z86J-3rbnA:
10.92