SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rbs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3rbs MYOMESIN-1
(Homo
sapiens) 		4 / 8 PHE A1418
ASN A1373
GLU A1371
GLY A1370
 None
 1.08A 1ykiA-3rbsA:
undetectable
1ykiB-3rbsA:
undetectable		 1ykiA-3rbsA:
24.81
1ykiB-3rbsA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3rbs MYOMESIN-1
(Homo
sapiens) 		4 / 8 PHE A1418
ASN A1373
GLU A1371
GLY A1370
 None
 1.07A 1ykiA-3rbsA:
undetectable
1ykiB-3rbsA:
undetectable		 1ykiA-3rbsA:
24.81
1ykiB-3rbsA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3rbs MYOMESIN-1
(Homo
sapiens) 		4 / 8 PHE A1418
ASN A1373
GLU A1371
GLY A1370
 None
 1.05A 1ykiC-3rbsA:
undetectable
1ykiD-3rbsA:
undetectable		 1ykiC-3rbsA:
24.81
1ykiD-3rbsA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3rbs MYOMESIN-1
(Homo
sapiens) 		4 / 7 LEU A1320
GLN A1319
PHE A1318
LEU A1269
 None
None
None
NO3  A1449 ( 4.0A)
 1.00A 2dysC-3rbsA:
undetectable
2dysJ-3rbsA:
undetectable		 2dysC-3rbsA:
18.39
2dysJ-3rbsA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3rbs MYOMESIN-1
(Homo
sapiens) 		3 / 3 ASP A1322
ASN A1327
PHE A1318
 None
 0.72A 5dsgB-3rbsA:
undetectable		 5dsgB-3rbsA:
16.39