SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rbt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		3 / 3 PHE A 120
PHE A 149
PHE A 201
 None
 0.87A 2od9A-3rbtA:
undetectable		 2od9A-3rbtA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		4 / 7 HIS A  33
PRO A 175
TYR A  31
HIS A  25
 None
 1.28A 2ombC-3rbtA:
undetectable
2ombD-3rbtA:
undetectable		 2ombC-3rbtA:
17.93
2ombD-3rbtA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		3 / 3 PHE A 120
PHE A 149
PHE A 201
 None
 0.87A 2qqgA-3rbtA:
undetectable		 2qqgA-3rbtA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		5 / 12 LEU A 128
GLY A 126
ILE A 142
PHE A 137
THR A 133
 None
 1.18A 3bjwF-3rbtA:
undetectable		 3bjwF-3rbtA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		5 / 12 PHE A 131
GLU A 140
GLY A 138
PHE A 135
GLY A 126
 None
 1.32A 3ps9A-3rbtA:
undetectable		 3ps9A-3rbtA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		3 / 3 MET A 168
GLN A 112
TYR A 108
 None
 1.00A 4udcA-3rbtA:
undetectable		 4udcA-3rbtA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		4 / 7 TRP A 204
GLN A 207
TYR A 160
TRP A 174
 None
 1.17A 5vlmG-3rbtA:
undetectable		 5vlmG-3rbtA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3rbt GLUTATHIONE
TRANSFERASE O1
(Bombyx
mori) 		4 / 7 TRP A 204
TYR A 160
TRP A 174
ASP A 206
 None
 1.10A 5vlmG-3rbtA:
undetectable		 5vlmG-3rbtA:
20.87