SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rc0'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IKE_A_HSMA190_1 (NITROPHORIN 4)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	3 / 3	ASP A 434 LEU A 167 LEU A 455	None	0.78A	1ikeA-3rc0A: undetectable	1ikeA-3rc0A: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N6C_A_SAMA402_0 (SET DOMAIN-CONTAINING PROTEIN 7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.82A	1n6cA-3rc0A: 6.7	1n6cA-3rc0A: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_B_ADNB1502_1 (CLASS B ACID PHOSPHATASE)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 7	GLU A 301 LEU A 293 THR A 284 TYR A 285	None None None SAM  A 484 (-4.8A)	1.24A	1rmtB-3rc0A: undetectable	1rmtB-3rc0A: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W0G_A_MYTA1499_1 (CYTOCHROME P450 3A4)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 6	ARG A 139 SER A 104 ILE A 105 ALA A 128	None	0.96A	1w0gA-3rc0A: undetectable	1w0gA-3rc0A: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_A_SAMA801_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 10	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.71A	2h21A-3rc0A: 29.4	2h21A-3rc0A: 25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_A_SAMA801_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	GLY A  76 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.14A	2h21A-3rc0A: 29.4	2h21A-3rc0A: 25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_B_SAMB802_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	7 / 11	GLY A  74 PRO A 148 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) None SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.86A	2h21B-3rc0A: 28.8	2h21B-3rc0A: 25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_B_SAMB802_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  76 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.17A	2h21B-3rc0A: 28.8	2h21B-3rc0A: 25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_C_SAMC803_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	7 / 11	GLY A  74 PRO A 148 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) None SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.87A	2h21C-3rc0A: 29.0	2h21C-3rc0A: 25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JN3_A_JN3A131_2 (FATTY ACID-BINDING PROTEIN, LIVER)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 6	ASN A 404 GLN A 467 ILE A 356 PHE A 354	EDO  A 477 ( 4.7A) None None None	1.10A	2jn3A-3rc0A: undetectable	2jn3A-3rc0A: 15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QR2_B_VK3B236_1 (PROTEIN (QUINONE REDUCTASE TYPE 2))	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 5	GLY A 106 GLY A 107 PHE A 203 PHE A 195	None	0.97A	2qr2A-3rc0A: undetectable 2qr2B-3rc0A: undetectable	2qr2A-3rc0A: 19.55 2qr2B-3rc0A: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VJ1_A_BEZA1303_0 (SARS CORONAVIRUS MAIN PROTEINASE)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	3 / 3	HIS A 155 MET A 157 MET A 221	None	1.39A	2vj1A-3rc0A: 0.6	2vj1A-3rc0A: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z9W_A_PXLA1197_1 (ASPARTATE AMINOTRANSFERASE)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLU A 227 LEU A 267 THR A 102 VAL A 242 SER A  99	None	1.49A	2z9wA-3rc0A: undetectable	2z9wA-3rc0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z9W_B_PXLB1197_1 (ASPARTATE AMINOTRANSFERASE)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLU A 227 LEU A 267 THR A 102 VAL A 242 SER A  99	None	1.48A	2z9wB-3rc0A: undetectable	2z9wB-3rc0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA607_1 (CHITINASE A)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 7	VAL A 318 SER A 419 THR A 370 LEU A 371	None	1.22A	3arrA-3rc0A: undetectable	3arrA-3rc0A: 19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MEK_A_SAMA510_0 (SET AND MYND DOMAIN-CONTAINING PROTEIN 3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.47A	3mekA-3rc0A: 12.2	3mekA-3rc0A: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OOI_A_SAMA237_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.93A	3ooiA-3rc0A: 6.0	3ooiA-3rc0A: 17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OPE_A_SAMA7_0 (PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.83A	3opeA-3rc0A: 6.4	3opeA-3rc0A: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QWP_A_SAMA510_0 (SET AND MYND DOMAIN-CONTAINING PROTEIN 3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.45A	3qwpA-3rc0A: 12.1	3qwpA-3rc0A: 22.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QXY_A_SAMA6734_0 (N-LYSINE METHYLTRANSFERASE SETD6)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	12 / 12	VAL A  72 ALA A  73 GLY A  74 TYR A  75 ALA A 222 TYR A 223 ASN A 251 HIS A 252 LEU A 253 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-4.6A) SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) None SAM  A 484 (-3.5A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.11A	3qxyA-3rc0A: 58.9	3qxyA-3rc0A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QXY_B_SAMB6735_0 (N-LYSINE METHYLTRANSFERASE SETD6 TRANSCRIPTION FACTOR P65)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	10 / 11	VAL A  72 ALA A  73 GLY A  74 TYR A  75 ALA A 222 TYR A 223 ASN A 251 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-4.6A) SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) None SAM  A 484 (-3.5A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.12A	3qxyB-3rc0A: 57.6 3qxyQ-3rc0A: undetectable	3qxyB-3rc0A: 100.00 3qxyQ-3rc0A: 2.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RC0_A_SAMA484_0 (N-LYSINE METHYLTRANSFERASE SETD6)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	11 / 11	VAL A  72 ALA A  73 GLY A  74 TYR A  75 ALA A 222 TYR A 223 ASN A 251 LEU A 253 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-4.6A) SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) None SAM  A 484 (-3.5A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.02A	3rc0A-3rc0A: 61.3	3rc0A-3rc0A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RC0_B_SAMB480_0 (N-LYSINE METHYLTRANSFERASE SETD6)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	12 / 12	VAL A  72 ALA A  73 GLY A  74 TYR A  75 ALA A 222 TYR A 223 ASN A 251 HIS A 252 LEU A 253 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-4.6A) SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) None SAM  A 484 (-3.5A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.11A	3rc0B-3rc0A: 57.9	3rc0B-3rc0A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S7B_A_SAMA1000_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.45A	3s7bA-3rc0A: 13.8	3s7bA-3rc0A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S7B_A_SAMA1000_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.18A	3s7bA-3rc0A: 13.8	3s7bA-3rc0A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S7F_A_SAMA1000_0 (N-LYSINE METHYLTRANSFERASE SMYD2 P53 PEPTIDE)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.45A	3s7fA-3rc0A: 4.9 3s7fI-3rc0A: undetectable	3s7fA-3rc0A: 22.32 3s7fI-3rc0A: 2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S7F_A_SAMA1000_0 (N-LYSINE METHYLTRANSFERASE SMYD2 P53 PEPTIDE)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.17A	3s7fA-3rc0A: 4.9 3s7fI-3rc0A: undetectable	3s7fA-3rc0A: 22.32 3s7fI-3rc0A: 2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S7J_A_SAMA1000_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.44A	3s7jA-3rc0A: 12.8	3s7jA-3rc0A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S7J_A_SAMA1000_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.20A	3s7jA-3rc0A: 12.8	3s7jA-3rc0A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SMT_A_SAMA1000_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	PRO A 148 ASN A 251 HIS A 252 TYR A 285 PHE A 299	None SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) SAM  A 484 (-3.5A)	0.65A	3smtA-3rc0A: 28.8	3smtA-3rc0A: 25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TG4_A_SAMA434_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.42A	3tg4A-3rc0A: 12.9	3tg4A-3rc0A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TG4_A_SAMA434_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.21A	3tg4A-3rc0A: 12.9	3tg4A-3rc0A: 22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AN2_A_EUIA1382_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	LEU A 468 LEU A 465 ILE A 356 ASP A 312 VAL A 420 GLY A 349	None	1.33A	4an2A-3rc0A: undetectable	4an2A-3rc0A: 22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BQF_B_QPSB951_1 (ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 8	ARG A 165 TRP A 159 GLU A 163 ARG A 450	None	1.10A	4bqfB-3rc0A: undetectable	4bqfB-3rc0A: 18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E47_A_SAMA401_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.81A	4e47A-3rc0A: 6.9	4e47A-3rc0A: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E47_B_SAMB800_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.82A	4e47B-3rc0A: 5.9	4e47B-3rc0A: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E47_C_SAMC800_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.84A	4e47C-3rc0A: 6.9	4e47C-3rc0A: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JDS_A_SAMA401_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.76A	4jdsA-3rc0A: 6.9	4jdsA-3rc0A: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JDS_B_SAMB401_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.77A	4jdsB-3rc0A: 6.6	4jdsB-3rc0A: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JDS_C_SAMC401_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.82A	4jdsC-3rc0A: 6.9	4jdsC-3rc0A: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JLG_A_SAMA401_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.85A	4jlgA-3rc0A: 6.5	4jlgA-3rc0A: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_A_NPSA602_1 (SERUM ALBUMIN)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 9	ALA A 271 ALA A 258 LEU A 260 SER A  37 VAL A  64	None	1.27A	4or0A-3rc0A: undetectable	4or0A-3rc0A: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XZK_A_AG2A700_1 (PUTATIVE NAD(+)--ARGININE ADP-RIBOSYLTRANSFERA SE VIS)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 7	SER A 104 ARG A 141 SER A 138 GLU A 132	None	1.35A	4xzkA-3rc0A: undetectable	4xzkA-3rc0A: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YND_A_SAMA505_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.44A	4yndA-3rc0A: 13.4	4yndA-3rc0A: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YND_A_SAMA505_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.16A	4yndA-3rc0A: 13.4	4yndA-3rc0A: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YNM_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.88A	4ynmB-3rc0A: 6.6	4ynmB-3rc0A: 20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YNP_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.78A	4ynpB-3rc0A: 6.6	4ynpB-3rc0A: 20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPA_A_SAMA3004_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.86A	4ypaA-3rc0A: 6.2	4ypaA-3rc0A: 19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPA_D_SAMD2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.87A	4ypaD-3rc0A: 6.5	4ypaD-3rc0A: 19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPU_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.82A	4ypuA-3rc0A: 6.4	4ypuA-3rc0A: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPU_B_SAMB2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.88A	4ypuB-3rc0A: 6.6	4ypuB-3rc0A: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ARF_A_SAMA1002_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.63A	5arfA-3rc0A: 0.4	5arfA-3rc0A: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ARF_A_SAMA1002_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.14A	5arfA-3rc0A: 0.4	5arfA-3rc0A: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ARG_A_SAMA1434_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.47A	5argA-3rc0A: 4.5	5argA-3rc0A: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ARG_A_SAMA1434_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.14A	5argA-3rc0A: 4.5	5argA-3rc0A: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AYF_A_SAMA401_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ALA A  73 GLY A  74 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.83A	5ayfA-3rc0A: 6.5	5ayfA-3rc0A: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CCL_A_SAMA504_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.43A	5cclA-3rc0A: 4.1	5cclA-3rc0A: 23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CCM_A_SAMA504_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.52A	5ccmA-3rc0A: 12.2	5ccmA-3rc0A: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXE_A_ESTA1000_1 (ESTROGEN RECEPTOR)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 8	LEU A 421 LEU A 416 HIS A 466 LEU A 465	None	0.85A	5dxeA-3rc0A: undetectable	5dxeA-3rc0A: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.83A	5jhnA-3rc0A: 7.4	5jhnA-3rc0A: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JHN_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.84A	5jhnB-3rc0A: 6.9	5jhnB-3rc0A: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIY_A_SAMA1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.82A	5jiyA-3rc0A: 7.0	5jiyA-3rc0A: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JIY_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.85A	5jiyB-3rc0A: 6.8	5jiyB-3rc0A: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJK_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.48A	5kjkA-3rc0A: 13.7	5kjkA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJK_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.21A	5kjkA-3rc0A: 13.7	5kjkA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJL_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.49A	5kjlA-3rc0A: 12.7	5kjlA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJL_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.24A	5kjlA-3rc0A: 12.7	5kjlA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJM_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.50A	5kjmA-3rc0A: 13.7	5kjmA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJM_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.21A	5kjmA-3rc0A: 13.7	5kjmA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJN_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.50A	5kjnA-3rc0A: 13.7	5kjnA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KJN_A_SAMA501_0 (N-LYSINE METHYLTRANSFERASE SMYD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	HIS A 155 HIS A 252 TYR A 285 TYR A 297 PHE A 299	None None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	1.23A	5kjnA-3rc0A: 13.7	5kjnA-3rc0A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KKL_B_SAMB8009_0 (PUTATIVE UNCHARACTERIZED PROTEIN,HISTONE H3.1 PEPTIDE,ZINC FINGER DOMAIN-CONTAINING PROTEIN)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A  75 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) None SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.51A	5kklB-3rc0A: 2.7	5kklB-3rc0A: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0K_A_SAMA1304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.85A	5t0kA-3rc0A: 6.9	5t0kA-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T0M_B_SAMB1205_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.82A	5t0mB-3rc0A: 6.9	5t0mB-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TEG_B_SAMB401_0 (HISTONE H4 MUTANT PEPTIDE WITH H4K20NORLEUCINE N-LYSINE METHYLTRANSFERASE KMT5A)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 10	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.79A	5tegB-3rc0A: 5.1 5tegE-3rc0A: undetectable	5tegB-3rc0A: 15.32 5tegE-3rc0A: 2.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TQR_B_SAMB8009_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EZH2, POLYCOMB PROTEIN SUZ12)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 10	GLY A  74 TYR A  75 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) None SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.85A	5tqrB-3rc0A: undetectable	5tqrB-3rc0A: 19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.78A	5ttfA-3rc0A: 6.6	5ttfA-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.74A	5ttfB-3rc0A: 6.8	5ttfB-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTF_D_SAMD1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.65A	5ttfD-3rc0A: 7.3	5ttfD-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTG_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.70A	5ttgA-3rc0A: 7.2	5ttgA-3rc0A: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TTG_B_SAMB1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.65A	5ttgB-3rc0A: 7.1	5ttgB-3rc0A: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUY_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.82A	5tuyA-3rc0A: 7.0	5tuyA-3rc0A: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUY_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.85A	5tuyB-3rc0A: 7.5	5tuyB-3rc0A: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUZ_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.71A	5tuzB-3rc0A: 6.8	5tuzB-3rc0A: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UPD_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.87A	5updA-3rc0A: 5.9	5updA-3rc0A: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V21_A_SAMA1804_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.88A	5v21A-3rc0A: 6.0	5v21A-3rc0A: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V37_A_SAMA504_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.47A	5v37A-3rc0A: 12.2	5v37A-3rc0A: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.73A	5v9iA-3rc0A: 6.5	5v9iA-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.73A	5v9iB-3rc0A: 6.9	5v9iB-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9I_C_SAMC1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.70A	5v9iC-3rc0A: 6.6	5v9iC-3rc0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9J_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.70A	5v9jA-3rc0A: 7.1	5v9jA-3rc0A: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V9J_B_SAMB1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.67A	5v9jB-3rc0A: 6.6	5v9jB-3rc0A: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSC_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.79A	5vscA-3rc0A: 6.9	5vscA-3rc0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSC_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.75A	5vscB-3rc0A: 7.6	5vscB-3rc0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSD_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.65A	5vsdB-3rc0A: 7.2	5vsdB-3rc0A: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSE_A_SAMA1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.78A	5vseA-3rc0A: 6.9	5vseA-3rc0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSE_B_SAMB1505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.76A	5vseB-3rc0A: 6.8	5vseB-3rc0A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VSF_B_SAMB3001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 12	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.73A	5vsfB-3rc0A: 7.1	5vsfB-3rc0A: 17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	3 / 3	ARG A  30 PHE A  90 LEU A  26	EDO  A 479 (-4.1A) None EDO  A 479 ( 4.1A)	0.92A	5x1bC-3rc0A: undetectable	5x1bC-3rc0A: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXD_A_SAMA501_0 (SMYD3 METHYLTRANSFERASE)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.44A	5xxdA-3rc0A: 12.1	5xxdA-3rc0A: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXG_A_SAMA502_0 (SMYD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.47A	5xxgA-3rc0A: 12.1	5xxgA-3rc0A: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXJ_A_SAMA505_0 (SMYD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.47A	5xxjA-3rc0A: 12.0	5xxjA-3rc0A: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJO_A_SAMA505_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	6 / 12	GLY A  74 ASN A 251 HIS A 252 TYR A 285 TYR A 297 PHE A 299	SAM  A 484 (-3.4A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A) None SAM  A 484 (-3.5A)	0.48A	5yjoA-3rc0A: 12.0	5yjoA-3rc0A: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CBZ_A_ESTA601_1 (ESTROGEN RECEPTOR)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 8	LEU A 421 LEU A 416 HIS A 466 LEU A 465	None	0.85A	6cbzA-3rc0A: undetectable	6cbzA-3rc0A: 11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CEN_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	5 / 11	GLY A  74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A) None SAM  A 484 (-4.8A)	0.87A	6cenA-3rc0A: 5.8	6cenA-3rc0A: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_B_STIB602_1 (TYROSINE-PROTEIN KINASE ABL1)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 6	LEU A 293 TYR A 297 VAL A  66 GLY A 286	None	0.83A	6hd4B-3rc0A: undetectable	6hd4B-3rc0A: 10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NM4_A_SAMA402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9)	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	4 / 7	ALA A  73 GLY A  74 TYR A 223 ASN A 251	SAM  A 484 (-3.3A) SAM  A 484 (-3.4A) SAM  A 484 (-3.6A) SAM  A 484 (-3.1A)	0.58A	6nm4A-3rc0A: 4.7	6nm4A-3rc0A: 18.34