SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rcc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 3rcc SORTASE SRTA
(Streptococcus
agalactiae) 		5 / 12 THR A 155
ILE A  76
ASP A  78
ALA A 137
ILE A 193
 None
 1.24A 3ddyA-3rccA:
undetectable		 3ddyA-3rccA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3rcc SORTASE SRTA
(Streptococcus
agalactiae) 		5 / 12 ILE A  74
ALA A 116
ILE A 159
LEU A 134
ILE A  76
 None
 0.99A 4kjjA-3rccA:
undetectable		 4kjjA-3rccA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3rcc SORTASE SRTA
(Streptococcus
agalactiae) 		4 / 5 HIS A 166
VAL A 167
GLU A 168
VAL A 162
 None
None
ZN  A 303 (-2.0A)
None
 1.21A 4p6vB-3rccA:
undetectable
4p6vE-3rccA:
undetectable		 4p6vB-3rccA:
15.82
4p6vE-3rccA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3rcc SORTASE SRTA
(Streptococcus
agalactiae) 		5 / 12 LEU A  94
ALA A  98
LEU A 181
LEU A 115
LEU A  83
 None
 1.22A 4zn7A-3rccA:
undetectable		 4zn7A-3rccA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3rcc SORTASE SRTA
(Streptococcus
agalactiae) 		4 / 6 PHE A  86
PRO A  69
THR A 100
ILE A  71
 None
 1.45A 5ih0A-3rccA:
undetectable		 5ih0A-3rccA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3rcc SORTASE SRTA
(Streptococcus
agalactiae) 		5 / 6 ILE A  76
MET A 141
ALA A 137
LEU A 134
ILE A 193
 None
 1.47A 5mvmB-3rccA:
undetectable
5mvmC-3rccA:
undetectable		 5mvmB-3rccA:
17.50
5mvmC-3rccA:
17.50