SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rcn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 9 ALA A 388
GLU A 364
VAL A 395
GLY A 392
GLY A 444
 None
 1.30A 1bcuH-3rcnA:
undetectable		 1bcuH-3rcnA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 VAL A 478
TRP A 480
TRP A  12
 None
 1.44A 1c4dA-3rcnA:
undetectable
1c4dB-3rcnA:
undetectable		 1c4dA-3rcnA:
3.88
1c4dB-3rcnA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 8 ASP A 296
HIS A 355
HIS A 354
HIS A 351
 None
 1.02A 1ei6D-3rcnA:
undetectable		 1ei6D-3rcnA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 4 VAL A 337
TRP A 343
TRP A 319
 SO4  A 554 (-3.9A)
None
None
 0.99A 1gmkA-3rcnA:
undetectable
1gmkB-3rcnA:
undetectable		 1gmkA-3rcnA:
3.88
1gmkB-3rcnA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 9 LEU A  46
VAL A  85
VAL A  29
TRP A 122
LEU A 106
 None
None
GOL  A 563 ( 4.3A)
None
None
 1.48A 1ikvA-3rcnA:
undetectable		 1ikvA-3rcnA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 8 VAL A 376
HIS A 341
SER A 342
VAL A 345
 None
 0.94A 1jtvA-3rcnA:
undetectable		 1jtvA-3rcnA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.72A 1rjoA-3rcnA:
undetectable		 1rjoA-3rcnA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.80A 1usqB-3rcnA:
undetectable		 1usqB-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.78A 1usqC-3rcnA:
undetectable		 1usqC-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.82A 1usqD-3rcnA:
undetectable		 1usqD-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.80A 1usqE-3rcnA:
undetectable		 1usqE-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 7 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.80A 1usqF-3rcnA:
undetectable		 1usqF-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.69A 1w2zA-3rcnA:
undetectable		 1w2zA-3rcnA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.70A 1w2zB-3rcnA:
undetectable		 1w2zB-3rcnA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.71A 1w2zC-3rcnA:
undetectable		 1w2zC-3rcnA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.68A 1w2zD-3rcnA:
undetectable		 1w2zD-3rcnA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 PRO A 418
GLY A 202
GLY A 527
ASP A 210
ARG A 463
 None
None
None
None
GOL  A 560 (-2.8A)
 1.21A 1wg8A-3rcnA:
undetectable		 1wg8A-3rcnA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 7 PRO A 470
LEU A 500
GLY A 497
LEU A 513
 None
 0.75A 1ya4B-3rcnA:
undetectable		 1ya4B-3rcnA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.86A 2jkjA-3rcnA:
undetectable		 2jkjA-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.86A 2jkjB-3rcnA:
undetectable		 2jkjB-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.86A 2jkjC-3rcnA:
undetectable		 2jkjC-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.83A 2jklB-3rcnA:
undetectable		 2jklB-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 7 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.83A 2jklE-3rcnA:
undetectable		 2jklE-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 PRO A 150
MET A 149
HIS A 147
ASP A 175
 None
 1.12A 2lh8A-3rcnA:
undetectable		 2lh8A-3rcnA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.71A 2oqeA-3rcnA:
undetectable		 2oqeA-3rcnA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.72A 2oqeB-3rcnA:
undetectable		 2oqeB-3rcnA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.72A 2oqeC-3rcnA:
undetectable		 2oqeC-3rcnA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.71A 2oqeD-3rcnA:
undetectable		 2oqeD-3rcnA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.72A 2oqeF-3rcnA:
undetectable		 2oqeF-3rcnA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.63A 2w0qA-3rcnA:
undetectable		 2w0qA-3rcnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 HIS A 355
HIS A 351
HIS A 354
 None
 0.64A 2w0qB-3rcnA:
undetectable		 2w0qB-3rcnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 5 HIS A 172
ASP A 242
HIS A 246
ASP A 312
 None
None
GOL  A 565 (-4.5A)
GOL  A 565 (-4.3A)
 1.25A 3c0zA-3rcnA:
undetectable		 3c0zA-3rcnA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 VAL A 298
LEU A 173
THR A 174
TRP A 179
VAL A 237
 None
 1.19A 3czvA-3rcnA:
undetectable
3czvB-3rcnA:
undetectable		 3czvA-3rcnA:
18.48
3czvB-3rcnA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 7 LEU A 166
VAL A 478
LEU A 403
LEU A 503
 None
 0.89A 3g8iA-3rcnA:
undetectable		 3g8iA-3rcnA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		10 / 12 ARG A 146
HIS A 172
ASP A 175
ASP A 242
HIS A 246
ASP A 312
TYR A 404
ASP A 406
TRP A 454
GLU A 456
 GOL  A 565 (-3.3A)
None
None
None
GOL  A 565 (-4.5A)
GOL  A 565 (-4.3A)
None
None
GOL  A 565 ( 4.5A)
GOL  A 565 ( 4.9A)
 0.39A 3lmyA-3rcnA:
40.1		 3lmyA-3rcnA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		11 / 12 ARG A 146
HIS A 172
ASP A 175
ASP A 242
HIS A 246
ASP A 312
GLU A 313
TRP A 362
TYR A 404
TRP A 454
GLU A 456
 GOL  A 565 (-3.3A)
None
None
None
GOL  A 565 (-4.5A)
GOL  A 565 (-4.3A)
GOL  A 565 (-3.2A)
None
None
GOL  A 565 ( 4.5A)
GOL  A 565 ( 4.9A)
 0.43A 3lmyB-3rcnA:
40.1		 3lmyB-3rcnA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 11 THR A  27
LEU A  54
LEU A  46
GLY A  47
VAL A 119
 None
 1.17A 3lxiB-3rcnA:
undetectable		 3lxiB-3rcnA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 8 ALA A 250
LEU A 257
ASP A 242
TYR A 291
 None
 1.01A 3qj7A-3rcnA:
undetectable
3qj7D-3rcnA:
undetectable		 3qj7A-3rcnA:
19.01
3qj7D-3rcnA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 6 TYR A 429
VAL A 478
THR A 424
THR A 423
 None
 1.13A 3tneA-3rcnA:
undetectable		 3tneA-3rcnA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 HIS A   5
ARG A 494
ARG A 486
SER A 481
ASP A 131
 None
 1.35A 3u40B-3rcnA:
undetectable
3u40C-3rcnA:
undetectable		 3u40B-3rcnA:
17.88
3u40C-3rcnA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 11 ARG A 486
SER A 481
ASP A 131
HIS A   5
ARG A 494
 None
 1.39A 3u40D-3rcnA:
undetectable
3u40E-3rcnA:
undetectable		 3u40D-3rcnA:
17.88
3u40E-3rcnA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 HIS A   5
ARG A 494
ARG A 486
SER A 481
ASP A 131
 None
 1.31A 3u40D-3rcnA:
undetectable
3u40E-3rcnA:
undetectable		 3u40D-3rcnA:
17.88
3u40E-3rcnA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 7 PRO A  56
ARG A  36
GLY A  37
PRO A  38
 GOL  A 563 (-3.6A)
None
GOL  A 564 (-3.9A)
GOL  A 564 (-4.0A)
 1.37A 3ucbB-3rcnA:
undetectable		 3ucbB-3rcnA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		3 / 3 TYR A  77
THR A 101
GLU A  75
 None
 0.83A 4df3A-3rcnA:
undetectable		 4df3A-3rcnA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 9 THR A 359
LEU A 309
VAL A 243
VAL A 298
LEU A 295
 None
 1.24A 4g1bC-3rcnA:
undetectable		 4g1bC-3rcnA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 LEU A 288
PHE A 344
GLN A 324
ALA A 325
GLY A 258
 None
None
SO4  A 553 (-4.1A)
None
None
 1.43A 4j7xA-3rcnA:
undetectable		 4j7xA-3rcnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 5 GLY A 202
SER A 203
ALA A 206
GLU A 526
 None
GOL  A 556 ( 4.9A)
None
None
 1.06A 4m93B-3rcnA:
undetectable
4m93C-3rcnA:
undetectable		 4m93B-3rcnA:
16.58
4m93C-3rcnA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 9 LEU A  54
GLY A  63
ALA A  62
ILE A  87
THR A  43
 None
None
None
None
GOL  A 563 ( 3.1A)
 1.12A 4njtD-3rcnA:
undetectable		 4njtD-3rcnA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 LEU A  46
VAL A  85
VAL A  29
TRP A 122
LEU A 106
 None
None
GOL  A 563 ( 4.3A)
None
None
 1.41A 5cymA-3rcnA:
undetectable		 5cymA-3rcnA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 LEU A  46
VAL A  85
VAL A  29
TRP A 122
LEU A 106
 None
None
GOL  A 563 ( 4.3A)
None
None
 1.38A 5cyqA-3rcnA:
undetectable		 5cyqA-3rcnA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 9 ARG A  36
ALA A  59
LEU A  35
LEU A  67
GLU A  34
 None
 1.24A 5dqfA-3rcnA:
undetectable		 5dqfA-3rcnA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 5 THR A 174
ALA A 145
TYR A 218
HIS A 172
 None
 1.15A 5ecmA-3rcnA:
undetectable		 5ecmA-3rcnA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 8 GLY A 311
GLY A 310
VAL A 314
HIS A 246
ASP A 175
 None
None
None
GOL  A 565 (-4.5A)
None
 1.46A 5f8yB-3rcnA:
undetectable		 5f8yB-3rcnA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 9 THR A  50
ALA A 110
ALA A 505
GLY A  48
ALA A  45
 None
 1.12A 5l5zK-3rcnA:
undetectable
5l5zL-3rcnA:
undetectable		 5l5zK-3rcnA:
15.75
5l5zL-3rcnA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 9 THR A  50
ALA A 110
ALA A 505
GLY A  48
ALA A  45
 None
 1.12A 5l5zY-3rcnA:
undetectable
5l5zZ-3rcnA:
undetectable		 5l5zY-3rcnA:
15.75
5l5zZ-3rcnA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 8 PHE A 431
PRO A 133
PRO A 483
PHE A 135
 None
 1.16A 5x23A-3rcnA:
undetectable		 5x23A-3rcnA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 10 LEU A 166
ILE A 453
PHE A 157
PHE A 466
LEU A 503
 None
None
None
GOL  A 560 (-4.6A)
None
 1.15A 5y7pB-3rcnA:
undetectable		 5y7pB-3rcnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 10 LEU A 166
ILE A 453
PHE A 157
PHE A 466
LEU A 503
 None
None
None
GOL  A 560 (-4.6A)
None
 1.18A 5y7pH-3rcnA:
undetectable		 5y7pH-3rcnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 4 ARG A 196
SER A 455
ASP A 143
HIS A 172
 None
 1.39A 5zhmA-3rcnA:
0.0		 5zhmA-3rcnA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		4 / 5 PRO A 239
VAL A 298
GLY A 346
VAL A 243
 None
 0.96A 6ak3B-3rcnA:
undetectable		 6ak3B-3rcnA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 3rcn BETA-N-ACETYLHEXOSAM
INIDASE
(Paenarthrobacter
aurescens) 		5 / 12 LEU A  46
VAL A  85
VAL A  29
TRP A 122
LEU A 106
 None
None
GOL  A 563 ( 4.3A)
None
None
 1.45A 6eliA-3rcnA:
undetectable		 6eliA-3rcnA:
8.22