SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rcz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3rcz SUMO-CONJUGATING
ENZYME UBC9
(Schizosaccharomy
ces
pombe) 		3 / 3 TRP B  53
GLU B 145
TYR B 144
 None
 1.25A 2a3aA-3rczB:
undetectable		 2a3aA-3rczB:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3rcz SUMO-CONJUGATING
ENZYME UBC9
(Schizosaccharomy
ces
pombe) 		3 / 3 THR B  70
PRO B  72
PRO B 105
 None
 0.85A 2d55C-3rczB:
undetectable		 2d55C-3rczB:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 3rcz DNA REPAIR PROTEIN
RAD60
SUMO-CONJUGATING
ENZYME UBC9
(Schizosaccharomy
ces
pombe) 		4 / 7 GLY B  44
LYS B  59
TRP A 383
TYR B  25
 None
 0.91A 3arrA-3rczB:
undetectable		 3arrA-3rczB:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 3rcz DNA REPAIR PROTEIN
RAD60
SUMO-CONJUGATING
ENZYME UBC9
(Schizosaccharomy
ces
pombe) 		4 / 7 GLY B  44
LYS B  59
TRP A 383
TYR B  25
 None
 0.87A 3aruA-3rczB:
undetectable		 3aruA-3rczB:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3rcz DNA REPAIR PROTEIN
RAD60
(Schizosaccharomy
ces
pombe) 		4 / 8 GLU A 344
ASP A 345
SER A 340
ARG A 339
 None
 1.13A 4uhxA-3rczA:
3.1		 4uhxA-3rczA:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 3rcz DNA REPAIR PROTEIN
RAD60
(Schizosaccharomy
ces
pombe) 		4 / 8 GLU A 344
ASP A 345
SER A 340
ARG A 339
 None
 1.13A 4uhxA-3rczA:
3.1		 4uhxA-3rczA:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 3rcz DNA REPAIR PROTEIN
RAD60
SUMO-CONJUGATING
ENZYME UBC9
(Schizosaccharomy
ces
pombe;
Schizosaccharomy
ces
pombe) 		5 / 12 ILE B  45
PRO B  21
SER A 402
PHE B  24
GLY B  44
 None
 1.24A 5il1A-3rczB:
undetectable		 5il1A-3rczB:
18.89