SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		5 / 12 THR A  11
LEU A 107
VAL A  23
PHE A  27
VAL A 105
 None
 1.34A 1q23B-3rd6A:
2.8		 1q23B-3rd6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		5 / 12 THR A  11
LEU A 107
VAL A  23
PHE A  27
VAL A 105
 None
 1.32A 1q23C-3rd6A:
3.1		 1q23C-3rd6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		5 / 10 THR A  11
LEU A 107
VAL A  23
PHE A  27
VAL A 105
 None
 1.35A 1q23E-3rd6A:
3.4		 1q23E-3rd6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		5 / 11 THR A  11
LEU A 107
VAL A  23
PHE A  27
VAL A 105
 None
 1.33A 1q23F-3rd6A:
3.2		 1q23F-3rd6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		5 / 11 THR A  11
LEU A 107
VAL A  23
PHE A  27
VAL A 105
 None
 1.35A 1q23I-3rd6A:
3.2		 1q23I-3rd6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		5 / 10 THR A  11
LEU A 107
VAL A  23
PHE A  27
VAL A 105
 None
 1.35A 1q23K-3rd6A:
3.1		 1q23K-3rd6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		5 / 11 THR A  11
LEU A 107
VAL A  23
PHE A  27
VAL A 105
 None
 1.36A 1q23L-3rd6A:
3.0		 1q23L-3rd6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		4 / 6 SER A 101
SER A  99
ALA A 131
SER A 130
 None
 0.96A 6bocA-3rd6A:
undetectable
6bocB-3rd6A:
undetectable
6bocC-3rd6A:
undetectable
6bocD-3rd6A:
undetectable		 6bocA-3rd6A:
8.23
6bocB-3rd6A:
8.23
6bocC-3rd6A:
8.23
6bocD-3rd6A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3rd6 MLL3558 PROTEIN
(Mesorhizobium
loti) 		4 / 6 SER A 101
SER A  99
ALA A 131
SER A 130
 None
 0.98A 6bocA-3rd6A:
undetectable
6bocB-3rd6A:
undetectable
6bocC-3rd6A:
undetectable
6bocD-3rd6A:
undetectable		 6bocA-3rd6A:
8.23
6bocB-3rd6A:
8.23
6bocC-3rd6A:
8.23
6bocD-3rd6A:
8.23