SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 ALA A 434
TRP A 145
ARG A 405
LEU A 363
 None
 1.14A 1gahA-3rdeA:
undetectable		 1gahA-3rdeA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 10 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.07A 1gwrA-3rdeA:
undetectable		 1gwrA-3rdeA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 LEU A 358
PHE A 415
TYR A 552
VAL A 409
 None
 1.17A 1ibgH-3rdeA:
undetectable		 1ibgH-3rdeA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 ILE A 290
GLY A 413
ALA A 404
TRP A 145
GLY A 423
 None
None
OYP  A 664 (-3.3A)
None
None
 1.10A 1kiaA-3rdeA:
undetectable		 1kiaA-3rdeA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 ILE A 290
GLY A 413
ALA A 404
TRP A 145
GLY A 423
 None
None
OYP  A 664 (-3.3A)
None
None
 1.10A 1kiaB-3rdeA:
undetectable		 1kiaB-3rdeA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 ILE A 290
GLY A 413
ALA A 404
TRP A 145
GLY A 423
 None
None
OYP  A 664 (-3.3A)
None
None
 1.11A 1kiaC-3rdeA:
undetectable		 1kiaC-3rdeA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 PHE A 394
ALA A 373
ALA A 369
MET A 368
LEU A 437
 None
 1.34A 1kt5A-3rdeA:
undetectable		 1kt5A-3rdeA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 ILE A 290
GLY A 413
ALA A 404
TRP A 145
GLY A 423
 None
None
OYP  A 664 (-3.3A)
None
None
 1.10A 1nbhB-3rdeA:
undetectable		 1nbhB-3rdeA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 ILE A 290
GLY A 413
ALA A 404
TRP A 145
GLY A 423
 None
None
OYP  A 664 (-3.3A)
None
None
 1.16A 1nbiB-3rdeA:
undetectable		 1nbiB-3rdeA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 10 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.08A 1pcgA-3rdeA:
undetectable		 1pcgA-3rdeA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 10 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.07A 1pcgB-3rdeA:
undetectable		 1pcgB-3rdeA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 10 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.17A 1qktA-3rdeA:
undetectable		 1qktA-3rdeA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.63A 1rjoA-3rdeA:
undetectable		 1rjoA-3rdeA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.58A 1rjoA-3rdeA:
undetectable		 1rjoA-3rdeA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 366
HIS A 361
HIS A 541
 FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.69A 1rkyA-3rdeA:
undetectable		 1rkyA-3rdeA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.56A 1rkyA-3rdeA:
undetectable		 1rkyA-3rdeA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.69A 1rkyA-3rdeA:
undetectable		 1rkyA-3rdeA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 LEU A 408
HIS A 366
ILE A 400
 OYP  A 664 (-3.7A)
FE2  A   1 ( 3.4A)
OYP  A 664 ( 4.6A)
 0.55A 1s9pB-3rdeA:
undetectable		 1s9pB-3rdeA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.71A 1v54A-3rdeA:
3.2		 1v54A-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.72A 1v54N-3rdeA:
undetectable		 1v54N-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.74A 1v55A-3rdeA:
1.7		 1v55A-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.74A 1v55N-3rdeA:
0.6		 1v55N-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.72A 1w2zA-3rdeA:
undetectable		 1w2zA-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.62A 1w2zA-3rdeA:
undetectable		 1w2zA-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 366
HIS A 361
HIS A 541
 FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.72A 1w2zB-3rdeA:
undetectable		 1w2zB-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.62A 1w2zB-3rdeA:
undetectable		 1w2zB-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.64A 1w2zB-3rdeA:
undetectable		 1w2zB-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.63A 1w2zC-3rdeA:
undetectable		 1w2zC-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.60A 1w2zC-3rdeA:
undetectable		 1w2zC-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 366
HIS A 361
HIS A 541
 FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.71A 1w2zD-3rdeA:
undetectable		 1w2zD-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.60A 1w2zD-3rdeA:
undetectable		 1w2zD-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.64A 1w2zD-3rdeA:
undetectable		 1w2zD-3rdeA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 PHE A 353
ARG A 364
ASN A 238
 None
 0.83A 1xzxX-3rdeA:
undetectable		 1xzxX-3rdeA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 ILE A 593
GLU A 357
HIS A 361
HIS A 545
 OYP  A 664 (-4.3A)
OYP  A 664 (-3.6A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.87A 1y93A-3rdeA:
undetectable		 1y93A-3rdeA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 11 VAL A 316
GLU A 276
ALA A 277
PRO A 249
PHE A 233
 None
 1.28A 2admB-3rdeA:
undetectable		 2admB-3rdeA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.71A 2dyrA-3rdeA:
undetectable		 2dyrA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 2dyrN-3rdeA:
undetectable		 2dyrN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.71A 2dysA-3rdeA:
undetectable		 2dysA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.66A 2dysN-3rdeA:
3.1		 2dysN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.71A 2eijA-3rdeA:
2.3		 2eijA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.72A 2eijN-3rdeA:
undetectable		 2eijN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.71A 2eikA-3rdeA:
undetectable		 2eikA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 2eikN-3rdeA:
0.6		 2eikN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.69A 2eilA-3rdeA:
undetectable		 2eilA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.70A 2eilN-3rdeA:
undetectable		 2eilN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 2eimN-3rdeA:
undetectable		 2eimN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.67A 2einA-3rdeA:
3.1		 2einA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.65A 2oqeA-3rdeA:
undetectable		 2oqeA-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.61A 2oqeA-3rdeA:
undetectable		 2oqeA-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.65A 2oqeB-3rdeA:
undetectable		 2oqeB-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.60A 2oqeB-3rdeA:
undetectable		 2oqeB-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.63A 2oqeC-3rdeA:
undetectable		 2oqeC-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.61A 2oqeC-3rdeA:
undetectable		 2oqeC-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.64A 2oqeD-3rdeA:
undetectable		 2oqeD-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.61A 2oqeD-3rdeA:
undetectable		 2oqeD-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.64A 2oqeF-3rdeA:
undetectable		 2oqeF-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.61A 2oqeF-3rdeA:
undetectable		 2oqeF-3rdeA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 PRO A 648
ASN A 642
ARG A 641
 None
 0.94A 2qeuB-3rdeA:
undetectable		 2qeuB-3rdeA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 5 LEU A 242
ASP A 352
MET A 303
LEU A 274
 None
 1.27A 2qxsB-3rdeA:
undetectable		 2qxsB-3rdeA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.65A 2w0qA-3rdeA:
undetectable		 2w0qA-3rdeA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.67A 2w0qA-3rdeA:
undetectable		 2w0qA-3rdeA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 366
HIS A 361
HIS A 541
 FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.71A 2w0qB-3rdeA:
undetectable		 2w0qB-3rdeA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.64A 2w0qB-3rdeA:
undetectable		 2w0qB-3rdeA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.66A 2w0qB-3rdeA:
undetectable		 2w0qB-3rdeA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 MET A 604
PRO A 602
ILE A 663
LEU A 546
 None
 1.02A 2wekB-3rdeA:
undetectable		 2wekB-3rdeA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.76A 2zxwA-3rdeA:
undetectable		 2zxwA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 2zxwN-3rdeA:
2.2		 2zxwN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 ARG A 364
ASP A 352
ASN A 544
 None
 0.82A 2zzmA-3rdeA:
undetectable		 2zzmA-3rdeA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.74A 3ablA-3rdeA:
2.2		 3ablA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 3ablN-3rdeA:
undetectable		 3ablN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 3abmN-3rdeA:
undetectable		 3abmN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 GLY A 478
LEU A 526
SER A 522
CYH A 527
 None
 0.75A 3aiaA-3rdeA:
undetectable		 3aiaA-3rdeA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.76A 3asoN-3rdeA:
undetectable		 3asoN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 8 LEU A 390
ILE A 534
TYR A 475
GLY A 608
 None
 0.71A 3b9lA-3rdeA:
undetectable		 3b9lA-3rdeA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 7 LEU A 304
ARG A 349
SER A 458
GLY A 236
 None
 1.02A 3hcnA-3rdeA:
undetectable		 3hcnA-3rdeA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.63A 3hiiA-3rdeA:
2.3		 3hiiA-3rdeA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.64A 3hiiA-3rdeA:
2.3		 3hiiA-3rdeA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 361
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.62A 3hiiB-3rdeA:
undetectable		 3hiiB-3rdeA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 541
HIS A 366
HIS A 545
 FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.65A 3hiiB-3rdeA:
undetectable		 3hiiB-3rdeA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 THR A 237
LYS A 189
GLU A 357
 None
None
OYP  A 664 (-3.6A)
 1.01A 3ijdB-3rdeA:
undetectable		 3ijdB-3rdeA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 GLY A 539
SER A 542
SER A 660
ILE A 472
LEU A 468
 None
 1.28A 3iv6D-3rdeA:
undetectable		 3iv6D-3rdeA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 5 ILE A 593
GLU A 357
HIS A 361
HIS A 545
 OYP  A 664 (-4.3A)
OYP  A 664 (-3.6A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.69A 3ljgA-3rdeA:
undetectable		 3ljgA-3rdeA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 ILE A 663
ALA A 662
THR A 397
ALA A 369
 None
 1.01A 3mdrB-3rdeA:
undetectable		 3mdrB-3rdeA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 GLY A 539
GLN A 540
ARG A 364
LEU A 466
ILE A 638
 None
 1.32A 3mnoA-3rdeA:
undetectable		 3mnoA-3rdeA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 GLY A 539
GLN A 540
ARG A 364
LEU A 466
ILE A 638
 None
 1.33A 3mnpA-3rdeA:
undetectable		 3mnpA-3rdeA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 GLN A 601
HIS A 366
HIS A 361
HIS A 541
 None
FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 1.08A 3nvcA-3rdeA:
undetectable		 3nvcA-3rdeA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.12A 3olsA-3rdeA:
undetectable		 3olsA-3rdeA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.13A 3olsB-3rdeA:
undetectable		 3olsB-3rdeA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.06A 3q95A-3rdeA:
undetectable		 3q95A-3rdeA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 7 PHE A 175
ASN A 401
ALA A 404
LEU A 597
 OYP  A 664 (-4.1A)
None
OYP  A 664 (-3.3A)
OYP  A 664 ( 4.9A)
 0.90A 3t3sC-3rdeA:
undetectable		 3t3sC-3rdeA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 7 TYR A 614
ILE A 391
PHE A 387
MET A 377
 None
 0.97A 3tvxB-3rdeA:
undetectable		 3tvxB-3rdeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 11 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.06A 3uudA-3rdeA:
undetectable		 3uudA-3rdeA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.72A 3wg7A-3rdeA:
2.3		 3wg7A-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.74A 3wg7N-3rdeA:
2.3		 3wg7N-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 ARG A 349
TRP A 551
GLY A 236
 None
 0.73A 4e7cA-3rdeA:
undetectable		 4e7cA-3rdeA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 TRP A 551
ASN A 642
TYR A 231
LEU A 647
 None
 1.50A 4f8yA-3rdeA:
undetectable
4f8yB-3rdeA:
undetectable		 4f8yA-3rdeA:
13.94
4f8yB-3rdeA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 8 HIS A 366
HIS A 361
HIS A 541
PHE A 167
 FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
None
 0.89A 4n16A-3rdeA:
undetectable		 4n16A-3rdeA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.05A 4pxmA-3rdeA:
undetectable		 4pxmA-3rdeA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.12A 4zn7A-3rdeA:
undetectable		 4zn7A-3rdeA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 11 LEU A 301
LEU A 242
LEU A 241
LEU A 304
MET A 315
 None
 1.34A 4zn7B-3rdeA:
undetectable		 4zn7B-3rdeA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.77A 5b1aN-3rdeA:
2.3		 5b1aN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 10 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.09A 5dxeB-3rdeA:
undetectable		 5dxeB-3rdeA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 PHE A 275
SER A 351
VAL A 348
ASP A 278
 None
 1.30A 5hesA-3rdeA:
undetectable		 5hesA-3rdeA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 10 LEU A 358
ALA A 433
LEU A 281
LEU A 282
HIS A 356
 None
 1.07A 5hyrA-3rdeA:
undetectable		 5hyrA-3rdeA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 VAL A 480
GLN A 525
CYH A 527
 None
 0.81A 5icxA-3rdeA:
undetectable
5icxE-3rdeA:
undetectable		 5icxA-3rdeA:
16.91
5icxE-3rdeA:
3.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 GLY A 236
ASN A 238
ALA A 558
ASN A 557
TYR A 231
 None
 1.39A 5kbwB-3rdeA:
1.8		 5kbwB-3rdeA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		5 / 12 GLY A 236
ASN A 238
ALA A 558
ASN A 557
VAL A 219
 None
 1.38A 5kbwB-3rdeA:
1.8		 5kbwB-3rdeA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 5 ILE A 593
GLU A 357
HIS A 361
HIS A 545
 OYP  A 664 (-4.3A)
OYP  A 664 (-3.6A)
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.87A 5n5kA-3rdeA:
undetectable		 5n5kA-3rdeA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 356
HIS A 361
HIS A 545
 None
FE2  A   1 ( 3.4A)
FE2  A   1 (-3.3A)
 0.77A 5oexA-3rdeA:
undetectable		 5oexA-3rdeA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 6 LEU A 179
SER A 178
PHE A 175
ASP A 174
 OYP  A 664 (-3.3A)
None
OYP  A 664 (-4.1A)
None
 1.15A 5om3A-3rdeA:
undetectable
5om3B-3rdeA:
undetectable		 5om3A-3rdeA:
11.23
5om3B-3rdeA:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 5z84A-3rdeA:
undetectable		 5z84A-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 5z84N-3rdeA:
2.2		 5z84N-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.75A 5z85A-3rdeA:
2.2		 5z85A-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.72A 5z85N-3rdeA:
undetectable		 5z85N-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.74A 5z86A-3rdeA:
2.3		 5z86A-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.76A 5z86N-3rdeA:
undetectable		 5z86N-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.75A 5zcoA-3rdeA:
1.7		 5zcoA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.71A 5zcoN-3rdeA:
2.2		 5zcoN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 5zcpA-3rdeA:
1.6		 5zcpA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.73A 5zcpN-3rdeA:
2.3		 5zcpN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.72A 5zcqA-3rdeA:
undetectable		 5zcqA-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 HIS A 545
HIS A 541
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
 0.71A 5zcqN-3rdeA:
undetectable		 5zcqN-3rdeA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 4 HIS A 541
HIS A 545
HIS A 361
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
 1.10A 5zrdC-3rdeA:
undetectable		 5zrdC-3rdeA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		4 / 4 HIS A 541
HIS A 545
HIS A 361
HIS A 366
 FE2  A   1 (-3.3A)
FE2  A   1 (-3.3A)
FE2  A   1 ( 3.4A)
FE2  A   1 ( 3.4A)
 1.11A 5zrdD-3rdeA:
undetectable		 5zrdD-3rdeA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE
(Sus
scrofa) 		3 / 3 ASN A 152
VAL A 661
HIS A 366
 None
None
FE2  A   1 ( 3.4A)
 0.79A 6a5yD-3rdeA:
undetectable		 6a5yD-3rdeA:
8.06