SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)
3rdj PROTEIN KINASE C
ALPHA TYPE

(Rattus
norvegicus)
5 / 12 LEU A 240
LEU A 164
THR A 212
ILE A 201
LEU A 200
None
1.09A 2jn3A-3rdjA:
undetectable
2jn3A-3rdjA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)
3rdj PROTEIN KINASE C
ALPHA TYPE

(Rattus
norvegicus)
3 / 3 ILE A 215
THR A 214
PRO A 221
None
0.44A 6ncsA-3rdjA:
undetectable
6ncsA-3rdjA:
20.00