SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3rdv CAP-GLY
DOMAIN-CONTAINING
LINKER PROTEIN 1
(Homo
sapiens) 		4 / 6 PHE A 118
ASN A  99
ILE A  90
GLY A 116
 None
 1.06A 1oniA-3rdvA:
undetectable
1oniB-3rdvA:
undetectable		 1oniA-3rdvA:
21.32
1oniB-3rdvA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3rdv CAP-GLY
DOMAIN-CONTAINING
LINKER PROTEIN 1
(Homo
sapiens) 		4 / 6 PHE A 118
ASN A  99
ILE A  90
GLY A 116
 None
 1.05A 1oniD-3rdvA:
undetectable
1oniF-3rdvA:
undetectable		 1oniD-3rdvA:
21.32
1oniF-3rdvA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3rdv CAP-GLY
DOMAIN-CONTAINING
LINKER PROTEIN 1
(Homo
sapiens) 		4 / 6 ARG A 107
GLY A 101
PRO A 113
LYS A 115
 None
 1.19A 2m2oB-3rdvA:
undetectable		 2m2oB-3rdvA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3rdv CAP-GLY
DOMAIN-CONTAINING
LINKER PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A  82
GLY A  78
ALA A  88
THR A 119
ILE A 117
 None
 1.44A 3ld6B-3rdvA:
undetectable		 3ld6B-3rdvA:
9.76