SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3re1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 ILE A 233
LEU A   8
ARG A  10
GLY A 185
LEU A 247
 None
 1.15A 1e7aB-3re1A:
undetectable		 1e7aB-3re1A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 LEU A 117
PRO A 129
VAL A 154
GLY A 153
 None
 0.99A 1hrkA-3re1A:
4.8		 1hrkA-3re1A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 LEU A 117
PRO A 129
VAL A 154
GLY A 153
 None
 1.01A 1hrkB-3re1A:
4.8		 1hrkB-3re1A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A 175
VAL A 220
LEU A 223
ARG A 164
 None
 1.02A 2oiqA-3re1A:
undetectable		 2oiqA-3re1A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 LEU A  18
LEU A   6
LEU A 247
ALA A 246
PHE A 214
 None
 1.22A 2vcvD-3re1A:
undetectable		 2vcvD-3re1A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 LEU A  18
LEU A   6
LEU A 247
ALA A 246
PHE A 214
 None
 1.24A 2vcvE-3re1A:
undetectable		 2vcvE-3re1A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 LEU A  18
LEU A   6
LEU A 247
ALA A 246
PHE A 214
 None
 1.28A 2vcvH-3re1A:
undetectable		 2vcvH-3re1A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 LEU A  18
LEU A   6
LEU A 247
ALA A 246
PHE A 214
 None
 1.24A 2vcvI-3re1A:
undetectable		 2vcvI-3re1A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 178
LEU A 186
GLY A 202
ALA A 201
LEU A 174
 None
 1.18A 3pghA-3re1A:
undetectable		 3pghA-3re1A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 LEU A 174
VAL A 188
LEU A 213
LEU A  32
LEU A 208
 None
 1.22A 4or0B-3re1A:
undetectable		 4or0B-3re1A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 LEU A   7
GLY A 202
ALA A 201
SER A 204
LEU A 208
 None
 1.12A 4ph9A-3re1A:
undetectable		 4ph9A-3re1A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 LEU A   7
GLY A 202
ALA A 201
SER A 204
LEU A 208
 None
 1.12A 4ph9B-3re1A:
undetectable		 4ph9B-3re1A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ALA A 246
GLY A 237
ILE A 233
VAL A 220
 None
 0.79A 4r21A-3re1A:
undetectable		 4r21A-3re1A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 LEU A   7
GLY A 202
ALA A 201
SER A 204
LEU A 208
 None
 1.14A 5jvzB-3re1A:
undetectable		 5jvzB-3re1A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 3re1 UROPORPHYRINOGEN-III
SYNTHETASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 ARG A 121
PHE A  87
LEU A 116
LEU A  98
 None
 1.29A 5veuH-3re1A:
undetectable		 5veuH-3re1A:
19.33