SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3re2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 PHE A  70
LEU A  74
ALA A 141
ALA A  32
LEU A 126
 None
 1.09A 1cbsA-3re2A:
undetectable		 1cbsA-3re2A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 GLU A 169
GLU A 178
TYR A 197
ILE A 186
 None
 0.88A 1qvtA-3re2A:
2.2		 1qvtA-3re2A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		3 / 3 ASP A 331
LYS A 330
ASP A 332
 None
 0.61A 4a7tA-3re2A:
undetectable		 4a7tA-3re2A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 378
LEU A 379
GLY A 410
SER A 408
LEU A 351
 None
 1.03A 4coxC-3re2A:
undetectable		 4coxC-3re2A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 6 SER A 228
ASP A 227
SER A 232
GLU A  42
 None
 0.99A 4eysA-3re2A:
undetectable		 4eysA-3re2A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 8 GLY A  39
LEU A 121
TYR A 118
ASN A 116
 None
 1.22A 4m5mA-3re2A:
undetectable		 4m5mA-3re2A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 378
LEU A 379
GLY A 410
SER A 408
LEU A 351
 None
 0.96A 4otyA-3re2A:
undetectable		 4otyA-3re2A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 378
LEU A 379
GLY A 410
SER A 408
LEU A 351
 None
 0.95A 4otyB-3re2A:
undetectable		 4otyB-3re2A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		3 / 3 ASP A 332
TYR A 328
TRP A 195
 None
 1.33A 4p7nA-3re2A:
undetectable		 4p7nA-3re2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 378
LEU A 379
GLY A 410
SER A 408
LEU A 351
 None
 0.97A 4rrwD-3re2A:
undetectable		 4rrwD-3re2A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 378
LEU A 379
GLY A 410
SER A 408
LEU A 351
 None
 0.97A 4rrzD-3re2A:
undetectable		 4rrzD-3re2A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 PHE A  63
LEU A 117
LEU A 121
ALA A 141
LEU A  74
 None
 1.07A 5iepA-3re2A:
undetectable		 5iepA-3re2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 VAL A 378
LEU A 379
GLY A 410
SER A 408
LEU A 351
 None
 1.01A 5ikqB-3re2A:
undetectable		 5ikqB-3re2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		5 / 12 LEU A 151
GLY A 130
ALA A 156
ASP A 127
PHE A 120
 None
 1.27A 5x6yC-3re2A:
undetectable		 5x6yC-3re2A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 4 PHE A 412
LEU A 473
LEU A 379
VAL A 406
 None
 1.28A 5xxiA-3re2A:
undetectable		 5xxiA-3re2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		4 / 5 ASN A  26
VAL A  37
LEU A  10
SER A   5
 None
 1.17A 6a7pA-3re2A:
undetectable		 6a7pA-3re2A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		3 / 3 LEU A 121
SER A 119
PHE A 120
 None
 0.65A 6fgcA-3re2A:
undetectable		 6fgcA-3re2A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 3re2 PREDICTED PROTEIN
(Nematostella
vectensis) 		3 / 3 ILE A 281
THR A 282
PRO A 295
 None
 0.64A 6ncsA-3re2A:
undetectable		 6ncsA-3re2A:
23.28