SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		5 / 12 LEU A  98
LEU A  37
ILE A  18
VAL A 148
VAL A 167
 None
 1.11A 2pnjA-3rf2A:
undetectable		 2pnjA-3rf2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		5 / 12 ALA A 154
GLY A 147
SER A 143
GLY A 161
GLY A 160
 None
 0.92A 3douA-3rf2A:
2.3		 3douA-3rf2A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 6 VAL A  27
LEU A  80
ILE A  46
ILE A  94
 None
 0.96A 3gcsA-3rf2A:
undetectable		 3gcsA-3rf2A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		5 / 12 ILE A  96
LEU A  98
ILE A  18
ALA A  17
ILE A  36
 None
 0.82A 3vrmA-3rf2A:
undetectable		 3vrmA-3rf2A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 5 ASP A 151
VAL A 133
GLY A 138
TYR A 132
 None
 1.39A 3w9tA-3rf2A:
undetectable		 3w9tA-3rf2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 5 ASP A 151
VAL A 133
GLY A 138
TYR A 132
 None
 1.39A 3w9tB-3rf2A:
undetectable		 3w9tB-3rf2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 5 ASP A 151
VAL A 133
GLY A 138
TYR A 132
 None
 1.38A 3w9tC-3rf2A:
undetectable		 3w9tC-3rf2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 5 ASP A 151
VAL A 133
GLY A 138
TYR A 132
 None
 1.39A 3w9tD-3rf2A:
undetectable		 3w9tD-3rf2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 5 ASP A 151
VAL A 133
GLY A 138
TYR A 132
 None
 1.38A 3w9tE-3rf2A:
undetectable		 3w9tE-3rf2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 5 ASP A 151
VAL A 133
GLY A 138
TYR A 132
 None
 1.38A 3w9tF-3rf2A:
undetectable		 3w9tF-3rf2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 5 ASP A 151
VAL A 133
GLY A 138
TYR A 132
 None
 1.39A 3w9tG-3rf2A:
undetectable		 3w9tG-3rf2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QE6_A_JN3A1001_1
(BILE ACID RECEPTOR)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		5 / 12 MET A  10
ALA A  13
ILE A  94
ILE A  46
TYR A 100
 None
 1.38A 4qe6A-3rf2A:
0.0		 4qe6A-3rf2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3rf2 30S RIBOSOMAL
PROTEIN S8
(Aquifex
aeolicus) 		4 / 7 GLU A  59
GLU A  58
TYR A  57
GLU A  60
 None
 1.21A 4r87I-3rf2A:
1.8		 4r87I-3rf2A:
18.78