SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rfb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3rfb PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 ALA A  34
LEU A 127
LEU A 125
LEU A 150
VAL A 147
 None
 1.17A 2bxeA-3rfbA:
undetectable		 2bxeA-3rfbA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3rfb PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 ASP A 141
TYR A 142
LYS A   6
 None
 1.03A 2othA-3rfbA:
undetectable		 2othA-3rfbA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 3rfb PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 PHE A  42
ASP A 139
TYR A  10
PRO A  43
 None
 1.28A 3jqaA-3rfbA:
undetectable		 3jqaA-3rfbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 3rfb PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 PHE A  42
ASP A 139
TYR A  10
PRO A  43
 None
 1.34A 3jqaB-3rfbA:
undetectable		 3jqaB-3rfbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 3rfb PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 PHE A  42
ASP A 139
TYR A  10
PRO A  43
 None
 1.30A 3jqaC-3rfbA:
undetectable		 3jqaC-3rfbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 3rfb PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 PHE A  42
ASP A 139
TYR A  10
PRO A  43
 None
 1.28A 3jqaD-3rfbA:
undetectable		 3jqaD-3rfbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3rfb PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 TYR A  51
ASP A 128
VAL A  46
GLU A 110
 SME  A6888 (-4.9A)
SME  A6888 (-2.7A)
None
SME  A6888 (-2.1A)
 0.90A 6djzB-3rfbA:
undetectable		 6djzB-3rfbA:
20.43