SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 3rg0 CALRETICULIN
(Mus
musculus) 		4 / 6 PRO A 204
ASP A 302
ASN A 304
TYR A 299
 None
 1.45A 1hpkA-3rg0A:
undetectable		 1hpkA-3rg0A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3rg0 CALRETICULIN
(Mus
musculus) 		4 / 5 PHE A  95
PHE A 330
PHE A  27
VAL A  97
 None
 1.12A 2lh6A-3rg0A:
undetectable		 2lh6A-3rg0A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 3rg0 CALRETICULIN
(Mus
musculus) 		4 / 8 ALA A  76
MET A 122
VAL A  93
PHE A  95
 None
 1.00A 4ltwA-3rg0A:
undetectable		 4ltwA-3rg0A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3rg0 CALRETICULIN
(Mus
musculus) 		5 / 12 GLN A 101
GLY A 106
ASP A 165
PHE A 327
VAL A  97
 None
 1.02A 4u8vB-3rg0A:
undetectable		 4u8vB-3rg0A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3rg0 CALRETICULIN
(Mus
musculus) 		3 / 3 ASN A 129
SER A 310
SER A  85
 None
 0.76A 5gsnA-3rg0A:
undetectable		 5gsnA-3rg0A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3rg0 CALRETICULIN
(Mus
musculus) 		5 / 9 VAL A 184
TYR A 172
VAL A 110
ASP A 135
GLY A 107
 None
 1.21A 5zniA-3rg0A:
undetectable		 5zniA-3rg0A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3rg0 CALRETICULIN
(Mus
musculus) 		5 / 9 LEU A 316
GLY A  65
LEU A  66
THR A 325
VAL A  97
 None
CA  A   1 ( 4.9A)
None
None
None
 1.09A 6czmA-3rg0A:
undetectable
6czmB-3rg0A:
undetectable		 6czmA-3rg0A:
22.48
6czmB-3rg0A:
22.48