SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rgh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3rgh FILAMIN-A
(Homo
sapiens) 		4 / 7 TYR A 229
GLN A 248
TYR A 221
ILE A 222
 CME  A 198 (-4.4A)
None
None
None
 1.31A 2ph9A-3rghA:
2.9
2ph9B-3rghA:
2.3		 2ph9A-3rghA:
18.55
2ph9B-3rghA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 3rgh FILAMIN-A
(Homo
sapiens) 		3 / 3 PHE A 243
CYH A 165
PHE A 181
 None
 1.13A 3cr5X-3rghA:
undetectable		 3cr5X-3rghA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rgh FILAMIN-A
(Homo
sapiens) 		4 / 4 VAL A 163
VAL A 240
TYR A 235
GLN A 238
 None
 1.25A 5qggA-3rghA:
undetectable		 5qggA-3rghA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rgh FILAMIN-A
(Homo
sapiens) 		4 / 4 VAL A 163
VAL A 240
TYR A 235
GLN A 238
 None
 1.22A 5qgoA-3rghA:
undetectable		 5qgoA-3rghA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rgh FILAMIN-A
(Homo
sapiens) 		4 / 4 VAL A 163
VAL A 240
TYR A 235
GLN A 238
 None
 1.24A 5qgpA-3rghA:
undetectable		 5qgpA-3rghA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rgh FILAMIN-A
(Homo
sapiens) 		4 / 4 VAL A 163
VAL A 240
TYR A 235
GLN A 238
 None
 1.21A 5qgqA-3rghA:
undetectable		 5qgqA-3rghA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3rgh FILAMIN-A
(Homo
sapiens) 		4 / 4 VAL A 163
VAL A 240
TYR A 235
GLN A 238
 None
 1.22A 5qhbA-3rghA:
undetectable		 5qhbA-3rghA:
20.50