SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rgq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3rgq PROTEIN-TYROSINE
PHOSPHATASE
MITOCHONDRIAL 1
(Mus
musculus) 		5 / 12 LEU A 215
GLY A 116
GLY A 203
ILE A 109
LEU A 187
 None
None
5P5  A 300 (-3.8A)
None
None
 1.11A 1p91B-3rgqA:
undetectable		 1p91B-3rgqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 3rgq PROTEIN-TYROSINE
PHOSPHATASE
MITOCHONDRIAL 1
(Mus
musculus) 		3 / 3 GLU A 161
PHE A 185
GLN A 162
 None
 1.02A 3r55A-3rgqA:
undetectable		 3r55A-3rgqA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3rgq PROTEIN-TYROSINE
PHOSPHATASE
MITOCHONDRIAL 1
(Mus
musculus) 		4 / 8 ASN A 140
GLN A 162
ASN A 150
THR A 151
 None
 1.45A 4d1yA-3rgqA:
undetectable
4d1yB-3rgqA:
undetectable		 4d1yA-3rgqA:
21.57
4d1yB-3rgqA:
21.57