SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N13_J_AG2J7013_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE BETA CHAIN PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE ALPHA CHAIN)	3rgu	FIMBRIAE-ASSOCIATED PROTEIN FAP1 (Streptococcus parasanguinis)	4 / 7	LEU A 194 LEU A 201 GLY A 202 MET A 133	None	0.92A	1n13G-3rguA: undetectable 1n13J-3rguA: undetectable	1n13G-3rguA: 18.94 1n13J-3rguA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QQC_K_AG2K671_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC))	3rgu	FIMBRIAE-ASSOCIATED PROTEIN FAP1 (Streptococcus parasanguinis)	4 / 8	MET A 133 LEU A 194 LEU A 201 GLY A 202	None	0.90A	2qqcH-3rguA: undetectable 2qqcK-3rguA: undetectable	2qqcH-3rguA: 21.05 2qqcK-3rguA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LCV_B_SAMB301_0 (SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM)	3rgu	FIMBRIAE-ASSOCIATED PROTEIN FAP1 (Streptococcus parasanguinis)	5 / 12	THR A 198 ILE A 189 ASP A 186 LEU A 176 LEU A 170	None	1.35A	3lcvB-3rguA: undetectable	3lcvB-3rguA: 21.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1N13_J_AG2J7013_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE BETA CHAIN;PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE ALPHA CHAIN","3rgu","FIMBRIAE-ASSOCIATED PROTEIN FAP1","Streptococcus parasanguinis",4,"LEU A 194;LEU A 201;GLY A 202;MET A 133","None","0.92A","1n13G-3rguA:undetectable;1n13J-3rguA:undetectable","1n13G-3rguA:18.94;1n13J-3rguA:18.94"],["2QQC_K_AG2K671_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC);PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE (EC 4.1.1.19) (PVLARGDC)","3rgu","FIMBRIAE-ASSOCIATED PROTEIN FAP1","Streptococcus parasanguinis",4,"MET A 133;LEU A 194;LEU A 201;GLY A 202","None","0.90A","2qqcH-3rguA:undetectable;2qqcK-3rguA:undetectable","2qqcH-3rguA:21.05;2qqcK-3rguA:19.53"],["3LCV_B_SAMB301_0","SISOMICIN-GENTAMICIN RESISTANCE METHYLASE SGM","3rgu","FIMBRIAE-ASSOCIATED PROTEIN FAP1","Streptococcus parasanguinis",5,"THR A 198;ILE A 189;ASP A 186;LEU A 176;LEU A 170","None","1.35A","3lcvB-3rguA:undetectable","3lcvB-3rguA:21.80"]]