SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3rh0 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		4 / 6 PHE A   6
ILE A  32
VAL A  30
ALA A  26
 None
 0.97A 2j5mA-3rh0A:
undetectable		 2j5mA-3rh0A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3rh0 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A  32
VAL A  78
TRP A  99
LEU A  80
ALA A 125
 None
 1.34A 2jj8C-3rh0A:
undetectable		 2jj8C-3rh0A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3rh0 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A  13
GLY A  10
LEU A  80
MET A  17
VAL A 115
 OCS  A   8 ( 4.5A)
OCS  A   8 ( 4.1A)
None
None
None
 1.12A 4f84A-3rh0A:
2.4		 4f84A-3rh0A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3rh0 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		4 / 6 GLY A  36
THR A  37
SER A  15
VAL A   7
 OCS  A   8 ( 3.1A)
OCS  A   8 ( 3.6A)
OCS  A   8 ( 2.6A)
OCS  A   8 ( 2.9A)
 1.01A 5ewuB-3rh0A:
undetectable		 5ewuB-3rh0A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 3rh0 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		3 / 3 LYS A  24
GLN A 118
ASN A 121
 None
 1.04A 5l2tA-3rh0A:
undetectable		 5l2tA-3rh0A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3rh0 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		3 / 3 ARG A  76
ARG A 122
ARG A  98
 None
 0.92A 5vcgA-3rh0A:
undetectable		 5vcgA-3rh0A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3rh0 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		3 / 3 SER A  34
SER A  15
ALA A  40
 None
OCS  A   8 ( 2.6A)
None
 0.66A 6dwnC-3rh0A:
undetectable		 6dwnC-3rh0A:
20.42