SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rh2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		3 / 3 PHE A  43
LEU A  32
SER A  11
 None
 0.90A 1e7aA-3rh2A:
2.8		 1e7aA-3rh2A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		5 / 12 GLU A  47
ARG A 105
PHE A  94
GLU A  20
ASP A 101
 None
 1.39A 2qeoA-3rh2A:
undetectable		 2qeoA-3rh2A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		4 / 6 TRP A 158
ILE A 159
LEU A 163
LEU A 176
 None
 0.83A 2rlfA-3rh2A:
undetectable
2rlfD-3rh2A:
undetectable		 2rlfA-3rh2A:
12.50
2rlfD-3rh2A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		4 / 4 ILE A   7
PHE A  43
ILE A   8
THR A  25
 None
 0.90A 3ia4A-3rh2A:
undetectable		 3ia4A-3rh2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		5 / 12 TYR A  96
GLY A 156
MET A 153
PHE A  65
LEU A  61
 None
UNL  A 301 ( 4.7A)
None
UNL  A 301 ( 4.2A)
None
 1.47A 4kosA-3rh2A:
0.9		 4kosA-3rh2A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		5 / 12 TYR A  96
GLY A 156
MET A 153
PHE A  65
LEU A  61
 None
UNL  A 301 ( 4.7A)
None
UNL  A 301 ( 4.2A)
None
 1.39A 4kovA-3rh2A:
undetectable		 4kovA-3rh2A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		5 / 12 TYR A  96
GLY A 156
MET A 153
PHE A  65
LEU A  61
 None
UNL  A 301 ( 4.7A)
None
UNL  A 301 ( 4.2A)
None
 1.33A 4kowA-3rh2A:
undetectable		 4kowA-3rh2A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		5 / 11 TYR A  96
GLY A 156
MET A 153
PHE A  65
LEU A  61
 None
UNL  A 301 ( 4.7A)
None
UNL  A 301 ( 4.2A)
None
 1.43A 4koxA-3rh2A:
undetectable		 4koxA-3rh2A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 3rh2 HYPOTHETICAL
TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Shewanella
amazonensis) 		4 / 6 GLY A 156
GLN A 117
TYR A  57
TYR A  96
 UNL  A 301 ( 4.7A)
UNL  A 301 ( 4.1A)
None
None
 1.23A 6ag0C-3rh2A:
undetectable		 6ag0C-3rh2A:
18.96