SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 GLU A 283
SER A 285
VAL A 242
TYR A 228
VAL A 179
 None
 1.48A 1x70A-3rh7A:
undetectable		 1x70A-3rh7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 GLU A 283
SER A 285
VAL A 242
TYR A 228
VAL A 179
 None
 1.48A 1x70B-3rh7A:
undetectable		 1x70B-3rh7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 270
SER A 269
SER A 195
LEU A 196
LEU A 210
 None
 1.05A 2xn5A-3rh7A:
undetectable		 2xn5A-3rh7A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 115
ALA A 152
GLY A 150
LEU A  77
TYR A 156
 None
 1.21A 2zifB-3rh7A:
undetectable		 2zifB-3rh7A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S68_A_SAMA228_1
(CATECHOL
O-METHYLTRANSFERASE)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ASN A  75
VAL A  76
ASN A  62
ALA A  57
PHE A  42
 None
None
FMN  A 321 (-3.5A)
FMN  A 321 (-3.4A)
None
 1.40A 3s68A-3rh7A:
0.0		 3s68A-3rh7A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 SER A 270
SER A 269
SER A 195
LEU A 196
LEU A 210
 None
 1.00A 4yiaA-3rh7A:
undetectable		 4yiaA-3rh7A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEE_B_RXMB601_0
(SCAFFOLD PROTEIN D13)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 9 PHE A  96
PHE A 111
PHE A  37
VAL A  99
GLN A  81
 None
 1.23A 6beeA-3rh7A:
0.0
6beeB-3rh7A:
0.0
6beeC-3rh7A:
0.0		 6beeA-3rh7A:
18.98
6beeB-3rh7A:
18.98
6beeC-3rh7A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEH_A_RPTA601_1
(SCAFFOLD PROTEIN D13)		 3rh7 HYPOTHETICAL
OXIDOREDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 PHE A  37
VAL A  99
PHE A  42
PHE A  96
PHE A 111
 None
 1.36A 6behA-3rh7A:
0.0
6behB-3rh7A:
0.0
6behC-3rh7A:
0.0		 6behA-3rh7A:
18.98
6behB-3rh7A:
18.98
6behC-3rh7A:
18.98