SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rh8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		4 / 6 ARG B 106
SER B  99
GLY B  97
THR B  96
 None
 1.08A 2f7fA-3rh8B:
undetectable		 2f7fA-3rh8B:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 9 ARG B 109
VAL B 145
GLY B 180
ILE B  74
ILE B 135
 FAD  B5201 (-4.3A)
None
FAD  B5201 (-3.8A)
FAD  B5201 (-4.9A)
FAD  B5201 ( 4.4A)
 1.13A 3ekqB-3rh8B:
undetectable		 3ekqB-3rh8B:
23.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 109
GLN B 112
ASN B 151
ASN B 161
ILE B  74
 FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-4.9A)
 1.37A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		6 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
ILE B 165
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 ( 4.1A)
FAD  B5201 (-4.1A)
 1.37A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 ASN B 107
CYH B 108
ARG B 109
GLN B 112
ASN B 151
ASN B 161
LEU B 163
ILE B 165
GLN B 182
 FAD  B5201 (-3.2A)
FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 ( 4.1A)
FAD  B5201 (-4.1A)
 0.57A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		6 / 12 SER B 178
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.93A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.32A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		8 / 12 ASN B 107
CYH B 108
ARG B 109
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.2A)
FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.59A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		6 / 12 SER B 178
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.06A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.11A 4r38A-3rh8B:
16.3		 4r38A-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.70A 4r38A-3rh8B:
16.3		 4r38A-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.13A 4r38B-3rh8B:
16.4		 4r38B-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		10 / 12 ASN B 107
CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-3.2A)
FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.68A 4r38B-3rh8B:
16.4		 4r38B-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.11A 4r38C-3rh8B:
16.4		 4r38C-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.67A 4r38C-3rh8B:
16.4		 4r38C-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.10A 4r38D-3rh8B:
16.5		 4r38D-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.67A 4r38D-3rh8B:
16.5		 4r38D-3rh8B:
31.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.21A 4r3aA-3rh8B:
12.7		 4r3aA-3rh8B:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		8 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.63A 4r3aA-3rh8B:
12.7		 4r3aA-3rh8B:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		8 / 12 CYH B 108
ARG B 109
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.60A 4r3aB-3rh8B:
12.5		 4r3aB-3rh8B:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		4 / 6 PRO B  60
GLN B  61
ARG B  57
ILE B 166
 None
 1.38A 6ef6A-3rh8B:
undetectable		 6ef6A-3rh8B:
16.34