SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3rh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A 168
PHE A 114
PHE A 115
ILE A 159
LEU A  82
 None
 1.12A 1dhfA-3rh9A:
undetectable		 1dhfA-3rh9A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 THR A 477
THR A 140
PRO A 479
 None
 0.87A 1fjaC-3rh9A:
undetectable		 1fjaC-3rh9A:
2.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 THR A 477
THR A 140
PRO A 479
 None
 0.87A 1fjaD-3rh9A:
undetectable		 1fjaD-3rh9A:
2.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 THR A 140
PRO A 479
THR A 477
 None
 0.87A 1i3wE-3rh9A:
undetectable		 1i3wE-3rh9A:
2.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 GLY A 285
LEU A 276
ASN A 279
THR A 387
GLY A 389
 None
 1.49A 1kvlA-3rh9A:
undetectable		 1kvlA-3rh9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 GLU A  87
TRP A 101
LYS A 120
 None
 1.41A 1qu2A-3rh9A:
undetectable		 1qu2A-3rh9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		6 / 10 LEU A 308
GLY A 283
GLY A 285
PRO A 370
VAL A 312
ILE A 277
 None
 1.40A 1sdtA-3rh9A:
undetectable		 1sdtA-3rh9A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 LEU A 308
ILE A 327
GLY A 284
GLY A 285
VAL A 372
 None
 0.85A 1sdtA-3rh9A:
undetectable		 1sdtA-3rh9A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 LEU A 308
ILE A 327
GLY A 284
GLY A 285
VAL A 372
 None
 0.82A 1sduA-3rh9A:
undetectable		 1sduA-3rh9A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.74A 1usqA-3rh9A:
undetectable		 1usqA-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.73A 1usqB-3rh9A:
undetectable		 1usqB-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.74A 1usqC-3rh9A:
undetectable		 1usqC-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.75A 1usqD-3rh9A:
undetectable		 1usqD-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.72A 1usqE-3rh9A:
undetectable		 1usqE-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.72A 1usqF-3rh9A:
undetectable		 1usqF-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 GLY A 453
GLY A 454
GLY A 459
PHE A 114
HIS A 437
 None
 1.21A 1wg8A-3rh9A:
3.8		 1wg8A-3rh9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 GLY A 453
GLY A 454
GLY A 459
PHE A 114
HIS A 437
 None
 1.18A 1wg8B-3rh9A:
3.8		 1wg8B-3rh9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 GLY A 468
GLY A 464
ILE A 122
ALA A 168
ALA A 171
 None
 0.89A 1x7pA-3rh9A:
undetectable
1x7pB-3rh9A:
undetectable		 1x7pA-3rh9A:
22.91
1x7pB-3rh9A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 THR A 477
THR A 140
PRO A 479
 None
 0.88A 209dC-3rh9A:
undetectable		 209dC-3rh9A:
2.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A 308
ILE A 327
GLY A 284
GLY A 285
VAL A 372
 None
 0.82A 2avvA-3rh9A:
undetectable		 2avvA-3rh9A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 8 SER A 176
LEU A  75
LEU A 469
LEU A 125
 None
 0.91A 2bfpD-3rh9A:
4.6		 2bfpD-3rh9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_E_SAME500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 SER A 176
GLY A  56
SER A  58
LEU A 200
TRP A  74
 None
 1.21A 2c2bE-3rh9A:
undetectable
2c2bF-3rh9A:
undetectable		 2c2bE-3rh9A:
23.47
2c2bF-3rh9A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 188
PHE A 192
LEU A 240
GLY A 150
SER A 176
 None
 1.28A 2e7fA-3rh9A:
undetectable		 2e7fA-3rh9A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 188
PHE A 192
LEU A 240
GLY A 150
SER A 176
 None
 1.28A 2e7fB-3rh9A:
undetectable		 2e7fB-3rh9A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.76A 2jkjA-3rh9A:
undetectable		 2jkjA-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.76A 2jkjB-3rh9A:
undetectable		 2jkjB-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.76A 2jkjC-3rh9A:
undetectable		 2jkjC-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.75A 2jkjE-3rh9A:
undetectable		 2jkjE-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.76A 2jklA-3rh9A:
undetectable		 2jklA-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.74A 2jklB-3rh9A:
undetectable		 2jklB-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.76A 2jklC-3rh9A:
undetectable		 2jklC-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.76A 2jklD-3rh9A:
undetectable		 2jklD-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.74A 2jklE-3rh9A:
undetectable		 2jklE-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.75A 2jklF-3rh9A:
undetectable		 2jklF-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 188
PHE A 192
LEU A 240
GLY A 150
SER A 176
 None
 1.25A 2ogyA-3rh9A:
undetectable		 2ogyA-3rh9A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 188
PHE A 192
LEU A 240
GLY A 150
SER A 176
 None
 1.28A 2ogyB-3rh9A:
undetectable		 2ogyB-3rh9A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A 308
ILE A 327
GLY A 284
GLY A 285
VAL A 372
 None
 0.79A 2r5pA-3rh9A:
undetectable		 2r5pA-3rh9A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A 308
ILE A 327
GLY A 284
GLY A 285
VAL A 372
 None
 0.79A 2r5pC-3rh9A:
undetectable		 2r5pC-3rh9A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 SER A  21
MET A  44
VAL A 218
ILE A  14
VAL A 177
 None
 1.24A 2uxpB-3rh9A:
undetectable		 2uxpB-3rh9A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A 168
PHE A 114
PHE A 115
ILE A 159
LEU A  82
 None
 1.11A 2w3bA-3rh9A:
undetectable		 2w3bA-3rh9A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A 168
PHE A 114
PHE A 115
ILE A 159
LEU A  82
 None
 1.13A 2w3bB-3rh9A:
undetectable		 2w3bB-3rh9A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A 168
PHE A 114
PHE A 115
ILE A 159
LEU A  82
 None
 1.13A 2w3mA-3rh9A:
undetectable		 2w3mA-3rh9A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 LEU A 166
ARG A  71
GLY A 147
MET A 227
 None
 1.07A 3hcrB-3rh9A:
2.2		 3hcrB-3rh9A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 LEU A  75
SER A 167
GLY A 173
ALA A 172
LEU A 125
 None
 1.13A 3n8yA-3rh9A:
undetectable		 3n8yA-3rh9A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 VAL A 148
ILE A 215
VAL A 218
LEU A 219
VAL A 225
 None
 0.98A 3w68C-3rh9A:
undetectable		 3w68C-3rh9A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 VAL A 148
ILE A 215
VAL A 218
LEU A 219
VAL A 225
 None
 0.98A 3w68D-3rh9A:
undetectable		 3w68D-3rh9A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 9 ILE A 189
LEU A   7
ILE A   2
MET A 321
ILE A  38
 None
 1.26A 3zosB-3rh9A:
undetectable		 3zosB-3rh9A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 188
PHE A 192
LEU A 240
GLY A 150
SER A 176
 None
 1.19A 4djfB-3rh9A:
undetectable		 4djfB-3rh9A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 ILE A  92
ALA A 190
GLU A   8
GLY A  12
GLU A  96
 None
 1.31A 4jlgB-3rh9A:
undetectable		 4jlgB-3rh9A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 GLY A 328
PRO A 329
GLN A 286
 None
 0.37A 4oltB-3rh9A:
undetectable		 4oltB-3rh9A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 MET A   1
MET A 321
TYR A  30
 None
 1.22A 4p6xI-3rh9A:
undetectable		 4p6xI-3rh9A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 GLY A 328
PRO A 329
GLN A 286
 None
 0.36A 4qwpB-3rh9A:
undetectable		 4qwpB-3rh9A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  75
SER A 167
GLY A 173
ALA A 172
LEU A 125
 None
 1.12A 4rrwA-3rh9A:
undetectable		 4rrwA-3rh9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  75
SER A 167
GLY A 173
ALA A 172
LEU A 125
 None
 1.11A 4rrwB-3rh9A:
undetectable		 4rrwB-3rh9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  75
SER A 167
GLY A 173
ALA A 172
LEU A 125
 None
 1.12A 4rrzA-3rh9A:
undetectable		 4rrzA-3rh9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  75
SER A 167
GLY A 173
ALA A 172
LEU A 125
 None
 1.11A 4rrzB-3rh9A:
undetectable		 4rrzB-3rh9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 7 GLU A 401
GLU A 402
PHE A 397
ARG A 425
 None
 0.91A 4twdF-3rh9A:
undetectable
4twdJ-3rh9A:
undetectable		 4twdF-3rh9A:
18.25
4twdJ-3rh9A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 4 ALA A 168
VAL A 473
GLY A 147
THR A 149
 None
 1.10A 4ubeA-3rh9A:
2.9		 4ubeA-3rh9A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 ILE A 262
PHE A 264
ILE A 404
GLU A 400
 None
 1.21A 4zzcA-3rh9A:
undetectable
4zzcB-3rh9A:
undetectable		 4zzcA-3rh9A:
20.31
4zzcB-3rh9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 6 ILE A 262
PHE A 264
ILE A 404
GLU A 400
 None
 1.24A 4zzcB-3rh9A:
undetectable
4zzcC-3rh9A:
undetectable		 4zzcB-3rh9A:
20.31
4zzcC-3rh9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 GLY A 232
GLY A 256
GLY A 459
LEU A 253
GLU A 183
 None
 0.96A 5c0oG-3rh9A:
4.1		 5c0oG-3rh9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 ILE A   2
ILE A 189
MET A  95
 None
 0.70A 5i9yA-3rh9A:
undetectable		 5i9yA-3rh9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  75
SER A 167
GLY A 173
ALA A 172
LEU A 125
 None
 1.08A 5ikrA-3rh9A:
undetectable		 5ikrA-3rh9A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  75
SER A 167
GLY A 173
ALA A 172
LEU A 125
 None
 0.97A 5jvzB-3rh9A:
undetectable		 5jvzB-3rh9A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 LEU A 308
ASP A 326
ILE A 327
GLY A 285
VAL A 372
 None
 0.92A 5kr1A-3rh9A:
undetectable		 5kr1A-3rh9A:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		4 / 8 ARG A 238
THR A 234
ILE A 241
GLY A 237
 None
 0.95A 5nzxA-3rh9A:
undetectable		 5nzxA-3rh9A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A  55
VAL A 177
VAL A 208
ASP A  48
GLY A  12
 None
 1.15A 5x24A-3rh9A:
undetectable		 5x24A-3rh9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))
(Marinobacter
hydrocarbonoclas
ticus) 		3 / 3 GLN A 427
TRP A 440
VAL A 418
 None
 0.91A 6auuA-3rh9A:
1.1		 6auuA-3rh9A:
18.64